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Nanostructured Monticellite: An Emerging Player in Tissue Engineering Publisher



Kalantari E1, 2 ; Naghib SM1 ; Naimijamal MR2 ; Esmaeili R3 ; Majidzadeha K3, 4 ; Mozafari M5
Authors

Source: Materials Today: Proceedings Published:2018


Abstract

Several types of calcium silicates have been significantly investigated for hard tissue engineering and replacement owing to their great potential for repair and regeneration. Here, a novel calcium silicate bioceramic (monticellite) was synthesized by sol-gel method and heat-treated at low temperature (1350°C). After physico-chemical characterization of the prepared bioceramic, bioactivity assessment was conducted via immersing in simulated body fluid (SBF) for investigating the apatite forming ability. The results exhibited that an apatite-like layer has formed on the surface of SBF-soaked sample after 14 days. In vitro evaluations showed that monticellite is biocompatible over mouse osteoblast-like cells (G292). In fact, the results shown that the monticellite bioceramics with good bioactivity had the ability G292 cell growth at a certain concentration range and exhibited good cytocompatibility. © 2018 Elsevier Ltd.
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