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Systematic Review: Effectiveness of Herbal Oral Care Products on Ventilator-Associated Pneumonia Publisher Pubmed



Mojtahedzadeh M1 ; Mashhadi Akbar Boojar M2, 3 ; Habtemariam S4 ; Nabavi SM5 ; Najafi A6 ; Ghahremanian A7, 8 ; Baktash M7, 8 ; Aghaabdollahian S9 ; Sureda A10 ; Bagheri M1
Authors

Source: Phytotherapy Research Published:2021


Abstract

Ventilator-associated pneumonia (VAP) resulting from bacterial infection is a prevalent medical problem in intensive care units (ICUs). The purpose of this study was to systematically review available studies on oral products employed to control and reduce VAP in patients undergoing tracheal intubation. This study was based on a systematic review of clinical trial data from science databases such as PubMed, Cochrane, Scopus, and Web of science. Articles were reviewed and selected according to defined criteria and assessed by the primary evaluation checklist. After a critical review of 3,143 search hits, only 18 relevant articles were finally selected for discussion. Our assessment revealed that chlorhexidine and some other oral herbal medications are beneficial in preventing VAP. Chlorhexidine oral dosage forms provide a remarkable role in oral health and prevention of VAP by decreasing the microbial flora in the mouth. Because of similar benefits and comparable effects, some herbal medicines can be suggested as a practical alternative to chlorhexidine. © 2021 John Wiley & Sons, Ltd.
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