Genetic Aspects of Idiopathic Asthenozoospermia As a Cause of Male Infertility

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Genetic Aspects of Idiopathic Asthenozoospermia As a Cause of Male Infertility Publisher Pubmed

Heidary Z¹ ; Saliminejad K¹ ; Zakidizaji M² ; Khorram Khorshid HR^{1, 3}

Source: Human Fertility Published:2020

Abstract

Infertility is a worldwide problem affecting about 15% of couples trying to conceive. Asthenozoospermia (AZS) is one of the major causes of male infertility, diagnosed by reduced sperm motility, and has no effective therapeutic treatment. To date, a few genes have been found to be associated with AZS in humans and mice, but in most of cases its molecular aetiology remains unknown. Genetic causes of AZS may include chromosomal abnormalities, specific mutations of nuclear and mitochondrial genes. However recently, epigenetic factors, altered microRNAs expression signature, and proteomics have shed light on the pathophysiological basis of AZS. This review article summarises the reported genetic causes of AZS. © 2018, © 2018 The British Fertility Society.

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Style	Citing Format
MLA	Heidary Z, et al.. "Genetic Aspects of Idiopathic Asthenozoospermia As a Cause of Male Infertility." Human Fertility, vol. 23, no. 2, 2020, pp. 83-92.
APA	Heidary Z, Saliminejad K, Zakidizaji M, Khorram Khorshid HR (2020). Genetic Aspects of Idiopathic Asthenozoospermia As a Cause of Male Infertility. Human Fertility, 23(2), 83-92.
Chicago	Heidary Z, Saliminejad K, Zakidizaji M, Khorram Khorshid HR. "Genetic Aspects of Idiopathic Asthenozoospermia As a Cause of Male Infertility." Human Fertility 23, no. 2 (2020): 83-92.
Harvard	Heidary Z et al. (2020) 'Genetic Aspects of Idiopathic Asthenozoospermia As a Cause of Male Infertility', Human Fertility, 23(2), pp. 83-92.
Vancouver	Heidary Z, Saliminejad K, Zakidizaji M, Khorram Khorshid HR. Genetic Aspects of Idiopathic Asthenozoospermia As a Cause of Male Infertility. Human Fertility. 2020;23(2):83-92.
BibTex	@article{ author = {Heidary Z and Saliminejad K and Zakidizaji M and Khorram Khorshid HR}, title = {Genetic Aspects of Idiopathic Asthenozoospermia As a Cause of Male Infertility}, journal = {Human Fertility}, volume = {23}, number = {2}, pages = {83-92}, year = {2020} }
RIS	TY - JOUR AU - Heidary Z AU - Saliminejad K AU - Zakidizaji M AU - Khorram Khorshid HR TI - Genetic Aspects of Idiopathic Asthenozoospermia As a Cause of Male Infertility JO - Human Fertility VL - 23 IS - 2 SP - 83 EP - 92 PY - 2020 ER -

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