Prevalence of Intestinal Parasitic Infections in Patients With Diabetes: A Systematic Review and Meta-Analysis Publisher Pubmed



Taghipour A¹ ; Javanmard E² ; Rahimi HM³ ; Abdoli A^{1, 4} ; Matin S⁵ ; Haghbin M⁶ ; Olfatifar M⁷ ; Mirjalali H³ ; Zali MR⁸
Source: International Health Published:2024

Abstract

Patients with diabetes are at an increased risk of intestinal parasitic infections (IPIs). We evaluated the pooled prevalence and OR of IPIs in patientswith diabetes through a systematic review and meta-analysis. A systematic search was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol for studies reporting IPIs in patients with diabetes through 1 August 2022. The collected data were analyzed using comprehensive meta-analysis software version 2. Thirteen case-control studies and nine crosssectional studies were included in this study. The overall prevalence of IPIs in patients with diabetes was calculated to be 24.4% (95% CI 18.8 to 31%). Considering the case-control design, the prevalence of IPIs in case (25.7%; 95% CI 18.4 to 34.5%) was higher than controls (15.5%; 95% CI 8.4 to 26.9%) and a significant correlationwas observed (OR, 1.80; 95% CI 1.08 to 2.97%). Moreover, a significant correlationwas seen in the prevalence of Cryptosporidium spp. (OR, 3.30%; 95% CI 1.86 to 5.86%), Blastocystis sp. (OR, 1.57%; 95% CI 1.11 to 2.22%) and hookworm (OR, 6.09%; 95% CI 1.11 to 33.41%) in the cases group. The present results revealed a higher prevalence of IPIs in patients with diabetes than in controls. Therefore, the results of this study suggest a proper health education program to preventing measures for the acquisition of IPIs in patients with diabetes. © The Author(s) 2023.