Introduction to Stem Cells and Immunity Publisher



Khanmohammadi S^{1, 2, 3} ; Fallahtafti P^{1, 4} ; Rezaei N^{2, 3, 5}
Source: Comprehensive Hematology and Stem Cell Research: Volume 1-5 Published:2024

Abstract

Stem cells constitute a category of undifferentiated cells capable of transforming into a multitude of cell types, each serving diverse functions in both humans and other organisms. Various studies have shown that stem cells are involved in modulating the immune system. Stem cells due to their capacity to self-renew and differentiate into specialized cell types play a crucial role in shaping the immune system's development, maintenance, and response to challenges. The immune system relies on various types of stem cells to maintain a delicate balance between defense against pathogens and prevention of autoimmune diseases. This chapter introduces different types of stem cells and delves into the intricate relationship between stem cells and the immune system, elucidating the dynamic interplay that underpins both homeostasis and disease. Also, the pivotal roles of various stem cell types in immune regulation, tissue repair, and regeneration are discussed, which sheds light on their immunomodulatory properties. © 2024 Elsevier Inc. All rights are reserved.