Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
The Recent Progress in the Early Diagnosis of Acute Myocardial Infarction Based on Myoglobin Biomarker: Nano-Aptasensors Approaches Publisher Pubmed



Asl SK1 ; Rahimzadegan M2, 3
Authors

Source: Journal of Pharmaceutical and Biomedical Analysis Published:2022


Abstract

Acute myocardial infarction (AMI) is one of the main health problems, leading to a major rate of mortality and morbidity. Given that myoglobin (Mb) is the earliest rising biomarker after AMI, recent studies have shown that Mb may be considered as a suitable biomarker for the detection of cardiac damage. Recently, aptamer-based biosensors (aptasensors) have attracted special attention for being accessible and their capability for sensitive detection of Mb. Moreover, the nano-aptasensors have provided new advances toward accurate detection of Mb. In this review, we provide an outline of the various types of optical and electrochemical-based aptasensors that have been developed for determination of Mb-related AMI. We also summarized recent developments in the applications of nano-aptasensors for recognition of Mb as an AMI biomarker. Future perspectives and challenges of aptamer-based Mb detection are discussed in brief as well. © 2022 Elsevier B.V.
Other Related Docs
9. Biosensors for Detection of Tau Protein As an Alzheimer's Disease Marker, International Journal of Biological Macromolecules (2020)
15. Nanomaterials and Optical Diagnosis of Hiv, Artificial Cells# Nanomedicine and Biotechnology (2016)