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Correlations Between Covid-19 and Burden of Dementia: An Ecological Study and Review of Literature Publisher Pubmed



Azarpazhooh MR1, 2, 3, 4 ; Amiri A4 ; Morovatdar N5 ; Steinwender S6 ; Rezaei Ardani A7 ; Yassi N8, 9 ; Biller J10 ; Stranges S3, 11, 19 ; Tokazebani Belasi M12 ; Neya SK12 ; Khorram B13 ; Sheikh Andalibi MS14 ; Arsangjang S15 ; Mokhber N16 Show All Authors
Authors
  1. Azarpazhooh MR1, 2, 3, 4
  2. Amiri A4
  3. Morovatdar N5
  4. Steinwender S6
  5. Rezaei Ardani A7
  6. Yassi N8, 9
  7. Biller J10
  8. Stranges S3, 11, 19
  9. Tokazebani Belasi M12
  10. Neya SK12
  11. Khorram B13
  12. Sheikh Andalibi MS14
  13. Arsangjang S15
  14. Mokhber N16
  15. Di Napoli M17, 18

Source: Journal of the Neurological Sciences Published:2020


Abstract

Introduction: Current evidence on the association between COVID-19 and dementia is sparse. This study aims to investigate the associations between COVID-19 caseload and the burden of dementia. Methods: We gathered data regarding burden of dementia (disability-adjusted life years [DALYs] per 100,000), life expectancy, and healthy life expectancy (HALE) from the Global Burden of Disease (GBD) 2017 study. We obtained COVID-19 data from Our World in Data database. We analyzed the association of COVID-19 cases and deaths with the burden of dementia using Spearman's rank correlation coefficient. Results: Globally, we found significant positive (p <.001) correlations between life expectancy (r = 0.60), HALE (r = 0.58), and dementia DALYs (r = 0.46) with COVID-19 caseloads. Likewise, we found similar correlations between life expectancy (r = 0.60), HALE (r = 0.58) and dementia DALYs (r = 0.54) with COVID-19 mortality. Conclusion: Health policymakers should clarify a targeted model of disease surveillance in order to reduce the dual burden of dementia and COVID-19. © 2020
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