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Hemagglutinin-Esterase Cannot Be Considered As a Candidate for Designing Drug Against Covid-19 Publisher Pubmed



Zandi M1, 2 ; Soltani S1, 2
Authors

Source: Molecular Diversity Published:2021


Abstract

We read with interest the article by Patel et al. on the identification of potential inhibitors of coronavirus hemagglutinin-esterase. The authors considered hemagglutinin-esterase as a glycoprotein of SARS-CoV-2 and selected hemagglutinin-esterase as a target to identify potential inhibitors using a combination of various computational approaches, and however, SARS-CoV-2 genome lacks hemagglutinin-esterase gene; thus, hemagglutinin-esterase does not exist in SARS-CoV-2 particle. Graphic abstract: [Figure not available: see fulltext.]. © 2021, The Author(s), under exclusive licence to Springer Nature Switzerland AG.