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Removal of Aflatoxin M1 in Milk Using Magnetic Laccase/Mos2/Chitosan Nanocomposite As an Efficient Sorbent Publisher Pubmed

Summary: Can nanoparticles clean milk? Study finds Fe3O4/Cs/MoS2/Lac NPs remove 68.5% of AFM1 from milk. #FoodSafety #Nanotechnology

Rezagholizadeshirvan A1 ; Ghasemi A2 ; Mazaheri Y3 ; Shokri S3 ; Fallahizadeh S4, 5 ; Alizadeh Sani M6 ; Mohtashami M7 ; Mahmoudzadeh M8 ; Sarafraz M9 ; Darroudi M10 ; Rezaei Z11 ; Shamloo E1
Authors

Source: Chemosphere Published:2024


Abstract

The current study tries to find the impact of the integration of laccase enzyme (Lac) onto magnetized chitosan (Cs) nanoparticles composed of molybdenum disulfide (MoS2 NPs) (Fe3O4/Cs/MoS2/Lac NPs) on the removal of AFM1 in milk samples. The Fe3O4/Cs/MoS2/Lac NPs were characterized by FT-IR, XRD, BET, TEM, FESEM, EDS, PSA, and VSM analysis. The cytotoxic activity of the synthesized nanoparticles in different concentrations was evaluated using the MTT method. The results show that the synthesized nanoparticles don't have cytotoxic activity at concentrations less than 20 mg/l. The ability of the prepared nanoparticles to remove AFM1 was compared by bare laccase enzyme, MoS2, and Fe3O4/Cs/MoS2 composite, indicating that the Fe3O4/Cs/MoS2/Lac NPs the highest adsorption efficiency toward AFM1. Besides, the immobilization efficiency of laccase with a concentration range of 0.5–2.0 was investigated, indicating that the highest activity recovery of 96.8% was obtained using 2 mg/ml laccase loading capacity. The highest removal percentage of AFM1 (68.5%) in the milk samples was obtained by the Fe3O4/Cs/MoS2/Lac NPs at a contact time of 1 h. As a result, Fe3O4/MoS2/Cs/Lac NPs can potentially be utilized as an effective sorbent with high capacity and selectivity to remove AFM1 from milk samples. © 2024 Elsevier Ltd
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Removal of Aflatoxin M1 in Milk Using Magnetic Laccase/Mos2/Chitosan Nanocomposite As an Efficient Sorbent
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