Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
A Quick Algorithmic Review on Management of Viral Infectious Diseases in Pediatric Solid Organ Transplant Recipients Publisher



Moghadamnia M1 ; Eshaghi H2 ; Alimadadi H3 ; Dashtikhavidaki S4
Authors

Source: Frontiers in Pediatrics Published:2023


Abstract

Pediatric solid organ transplant is a life-saving procedure for children with end-stage organ failure. Viral infections are a common complication following pediatric solid organ transplantation (SOT), which can lead to increased morbidity and mortality. Pediatric solid organ transplant recipients are at an increased risk of viral infections due to their immunosuppressed state. The most commonly encountered viruses include cytomegalovirus (CMV), Epstein-Barr virus (EBV), herpes simplex virus (HSV), varicella-zoster virus (VZV), adenoviruses, and BK polyomavirus. Prevention strategies include vaccination prior to transplantation, post-transplant prophylaxis with antiviral agents, and preemptive therapy. Treatment options vary depending on the virus and may include antiviral therapy and sometimes immunosuppression modification. This review provides a Quick Algorithmic overview of prevention and treatment strategies for viral infectious diseases in pediatric solid organ transplant recipient. 2023 Moghadamnia, Eshaghi, Alimadadi and Dashti-Khavidaki.
Other Related Docs
20. Bk Viremia Among Iranian Renal Transplant Candidates, Iranian Journal of Pathology (2016)