Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Immediate Hypersensitivity Reaction to Levetiracetam: A Case Report Study Publisher Pubmed



Hosseini MS1 ; Namazi S1, 2
Authors

Source: DARU# Journal of Pharmaceutical Sciences Published:2024


Abstract

Background: Anticonvulsant drugs are one of the most common causes of delayed hypersensitivity reactions, such as drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN). These reactions are more prevalent with aromatic anticonvulsant drugs such as phenytoin and carbamazepine. However, immediate hypersensitivity reactions such as urticaria, angioedema, and anaphylaxis with anticonvulsant drugs are rare. We describe a 51-year-old woman who developed spreading skin rashes on her wrists with urticaria and pruritus 24 h after receiving intravenous levetiracetam. Conclusion: Clinicians should be aware of immediate hypersensitivity reactions with intravenous levetiracetam. Graphical abstract: (Figure presented.) © The Author(s), under exclusive licence to Tehran University of Medical Sciences 2023.
Related Docs
View other Related Docs
1. Patterns of Antiepileptic Drug Reactions in Children: A Multicenter Study, Iranian Journal of Child Neurology (2022)
2. Evaluation of Lymphocyte Transformation Test Results in Patients With Delayed Hypersensitivity Reactions Following the Use of Anticonvulsant Drugs, International Archives of Allergy and Immunology (2016)
3. Dress Syndrome Induced by Sorafenib in a Patient With Medullary Thyroid Cancer: A Case Report, Hospital Pharmacy (2021)
Experts (# of related papers)
View all Related Experts
Zahra Saffarian (2)
Vahideh Sadat Lajevardi (2)
Other Related Docs
4. Real Life Management of Chronic Urticaria: Multicenter and Cross Sectional Study on Patients and Dermatologists in Iran, Dermatologic Therapy (2019)
5. Dress Syndrome Presents As Leukoencephalopathy, Turkish Journal of Pediatrics (2015)
6. Diagnosis and Selection of Alternative Antibiotics in Beta-Lactams Hypersensitivity Reactions: Current Recommendations and Challenges, International Immunopharmacology (2023)
7. Hla-B*1502 in Iranian Children With Anticonvulsant Drugs-Induced Skin Reactions, Iranian Journal of Child Neurology (2017)
8. B-Cell Acute Lymphoblastic Leukemia Associated With Hypereosinophilia: A Case Report and Brief Literature Review, SAGE Open Medical Case Reports (2024)
9. A Study of Severe Cutaneous Adverse Drug Reactions in Iranian Patients, Iranian Journal of Dermatology (2021)
10. Update of the Diagnosis and Treatment of Urticaria: Iranian Society of Dermatology Clinical Practice Guideline, Iranian Journal of Dermatology (2023)