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Consensus Recommendations for Diagnosis and Treatment of Multiple Sclerosis: 2023 Revision of the Menactrims Guidelines Publisher Pubmed



Yamout B1 ; Aljumah M2 ; Sahraian MA3 ; Almalik Y4 ; Khaburi JA5 ; Shalaby N6 ; Aljarallah S7 ; Bohlega S8 ; Dahdaleh M9 ; Almahdawi A10 ; Khoury SJ11 ; Koussa S12 ; Slassi E13 ; Daoudi S14 Show All Authors
Authors
  1. Yamout B1
  2. Aljumah M2
  3. Sahraian MA3
  4. Almalik Y4
  5. Khaburi JA5
  6. Shalaby N6
  7. Aljarallah S7
  8. Bohlega S8
  9. Dahdaleh M9
  10. Almahdawi A10
  11. Khoury SJ11
  12. Koussa S12
  13. Slassi E13
  14. Daoudi S14
  15. Aref H15
  16. Mrabet S16
  17. Zeineddine M17
  18. Zakaria M18
  19. Inshasi J19
  20. Gouider R16
  21. Alroughani R20

Source: Multiple Sclerosis and Related Disorders Published:2024


Abstract

With evolving diagnostic criteria and the advent of new oral and parenteral therapies for Multiple Sclerosis (MS), most current diagnostic and treatment algorithms need revision and updating. The diagnosis of MS relies on incorporating clinical and paraclinical findings to prove dissemination in space and time and exclude alternative diseases that can explain the findings at hand. The differential diagnostic workup should be guided by clinical and laboratory red flags to avoid unnecessary tests. Appropriate selection of MS therapies is critical to maximize patient benefit. The current guidelines review the current diagnostic criteria for MS and the scientific evidence supporting treatment of acute relapses, radiologically isolated syndrome, clinically isolated syndrome, relapsing remitting MS, progressive MS, pediatric cases and pregnant women. The purpose of these guidelines is to provide practical recommendations and algorithms for the diagnosis and treatment of MS based on current scientific evidence and clinical experience. © 2024 Elsevier B.V.
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