Legume Intake and Risk of Nonalcoholic Fatty Liver Disease Publisher Pubmed



Bahrami A¹ ; Teymoori F¹ ; Eslamparast T² ; Sohrab G² ; Hejazi E² ; Poustchi H³ ; Hekmatdoost A²
Source: Indian Journal of Gastroenterology Published:2019

Abstract

Background: It is known that diet plays a pivotal role in the pathogenesis and management of nonalcoholic fatty liver disease (NAFLD); however, the knowledge on the role of different food groups such as legumes is not enough. Methods: We designed this study to assess the relationship between legume intake and risk of NAFLD in framework of a case-control study among Tehrani adults. One hundred and ninety-six newly diagnosed patients with NAFLD and 803 controls were studied, and their dietary intake was assessed using a valid and reliable food frequency questionnaire. Conditional logistic regression was used to determine the odds ratio (OR) of NAFLD per increase of one serving/week dietary legumes, lentil, and beans adjusting for potential confounders. Results: In energy-adjusted model, greater intake of legumes, lentils, and beans was associated with a lower risk of NAFLD. These risk associations remained significant after adjusting for all known risk factors of NAFLD. OR of NAFLD in adjusted models for higher dietary intake of legumes, lentils, and beans were 0.73 (0.64–0.84), 0.61 (0.46–0.78), and 0.35 (0.17–0.74), respectively. Conclusion: Our findings suggest that higher intake of total legumes (beans, lentils, and peas) was associated with lower risk of NAFLD. [Figure not available: see fulltext.]. © 2019, Indian Society of Gastroenterology.