Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
The Role of Dna Methylation in Cancer Publisher



Shahkarami S1, 2, 3 ; Zoghi S1, 4, 5, 6 ; Rezaei N7, 8, 9
Authors

Source: Cancer Immunology: A Translational Medicine Context# Second Edition Published:2020


Abstract

DNA methylation is a highly characterized epigenetic mechanism, which plays a fundamental role in epigenetic disorders such as cancers. A large number of DNA methylation analysis strategies are available for assessing the DNA methylation status in order to define unique DNA methylation features and employing them as beneficial biomarkers for diagnosis, prognosis, and residual disease detecting. Furthermore, cancer therapy approaches hold promise for effective interventions with respect to reversible nature of DNA methylation aberrations. © Springer Nature Switzerland AG 2020.
Related Docs
View other Related Docs
1. Methylation in Colorectal Cancer, Epigenetics Territory and Cancer (2015)
2. Dna Methylation in Human Diseases, Heliyon (2024)
3. Epi-Drugs and Epi-Mirs: Moving Beyond Current Cancer Therapies, Current Cancer Drug Targets (2016)
Experts (# of related papers)
View all Related Experts
Hamid Reza Mirzaei (2)
Seyed Mohammad Tavangar (2)
Other Related Docs
4. Sirna and Epigenetic Aberrations in Ovarian Cancer, Journal of Cancer Research and Therapeutics (2016)
5. Future Challenges and Prospects for the Epigenetics of Autoimmunity, The Epigenetics of Autoimmunity (2018)
6. Detection of Aberrant Methylated Sept9 and Ntrk3 Genes in Sporadic Colorectal Cancer Patients As a Potential Diagnostic Biomarker, Oncology Letters (2016)
7. Epigenetic Modifications in Gastric Cancer: Focus on Dna Methylation, Gene (2020)
8. Circulating Ctdna Methylation Quantification of Two Dna Methyl Transferases in Papillary Thyroid Carcinoma, Journal of Cellular Biochemistry (2019)
9. Epigenetics and Three Main Clinical Aspects of Breast Cancer Management, Epigenetics Territory and Cancer (2015)
10. A Systematic Review and Meta-Analysis of the Dna Methylation in Colorectal Cancer Among Iranian Population, Gene Reports (2021)
11. Methylation of Fbn1, Spg20, Itf2, Runx3, Snca, Mlh1, and Sept9 Genes in Circulating Cell-Free Dna As Biomarkers of Colorectal Cancer, Cancer Biomarkers (2022)
12. Effect of Dnmt3a R882h Hot Spot Mutations on Ddx43 Promoter Methylation in Acute Myeloid Leukemia, BioMed Research International (2024)
13. A Mutational and Expressional Analysis of Dnmt3a in Acute Myeloid Leukemia Cytogenetic Subgroups, Hematology (2015)
14. Epigenetic of Retinoic Acid Receptor ß2 Gene in Breast Cancer, Epigenetics Territory and Cancer (2015)
15. Environmental Toxicants, Incidence of Degenerative Diseases, and Therapies From the Epigenetic Point of View, Archives of Toxicology (2017)
16. Regulation of Dna Methylation Machinery by Epi-Mirnas in Human Cancer: Emerging New Targets in Cancer Therapy, Cancer Gene Therapy (2021)
17. The Gene Expression Profile and Dna Methylation Pattern of Cdh1 and Dnmt1 Genes in Acute Promyelocytic Leukemia (Apl), Reports of Biochemistry and Molecular Biology (2020)
18. Promoter Methylation Status and Expression Levels of Rassf1a Gene in Different Phases of Acute Lymphoblastic Leukemia (All), International Journal of Hematology-Oncology and Stem Cell Research (2021)
19. Promoter Methylation of Four Tumor Suppressor Genes in Human Papillary Thyroid Carcinoma, Iranian Journal of Pathology (2019)
20. Methylation Analysis of P16, Rassf1a, Rprm, and Runx3 in Circulating Cell-Free Dna for Detection of Gastric Cancer: A Validation Study, Avicenna Journal of Medical Biotechnology (2020)