Translation and Psychometric Evaluation of the Persian Version of the Treatment Satisfaction With Medicines Questionnaire (Satmed-Q) in Chronically-Ill Patients Publisher



Khatib A ; Barkhordari Sharifabad M ; Pazhavand M M
Source: Physiology and Pharmacology (Iran) Published:2026

Abstract

Introduction: It is helpful to know the rate of satisfaction with treatment for predicting treatment adherence and compliance with medical advice. Thus, measuring this parameter is important both in daily clinical care and in biomedical research. Due to the unavailability of an instrument to evaluate treatment satisfaction with medicines in Persian, this study dealt with translating and psychometrically evaluating the Persian version of the Treatment Satisfaction with Medicines Questionnaire (SATMED-Q) in chronically ill patients. Methods: This descriptive cross-sectional study was performed in two stages: translation and psychometric evaluation. After obtaining permission from the developer of the questionnaire, the process of translation was carried out based on Wild’s model (2005). Face validity (20 chronically-ill patients), qualitative content validity (10 experts), and construct validity including confirmatory factor analysis (225 chronically ill patients), were employed to establish the validity of the questionnaire. Further, the reliability of the instrument was established by determining the internal consistency and intra-class correlation (51 chronically ill patients). The data were analyzed using SPSS23 and LISREL8.5. Results: To assess face and content validity, the questionnaire items underwent modifications based on feedback from patients and experts. According to confirmatory factor analysis, the fit index values demonstrated an appropriate alignment between the model and data. The subscales’Cronbach’s α coefficients ranged from 0.905 to 0.985, while the entire questionnaire’s Cronbach’s α coefficient was 0.875. Additionally, the test-retest reliability, as measured via the intra-class correlation coefficient, was determined to be 0.739 over two weeks. Conclusion: The Persian version of the SATMED-Q has appropriate face, content, construct, and criterion-referenced validity as well as reliability for assessing treatment satisfaction with medicines in chronically ill patients. It is also advisable to use it in clinical studies, clinical settings, education, and management. © 2026, Iranian Society of Physiology and Pharmacology. All rights reserved.