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Alk-Positive Histiocytosis Involving the Cavernous Sinus: A Deceptive Radiologic Mimic of Meningioma Publisher



Alizadeh M1 ; Ravindran A2 ; Chkheidze R3 ; Goyal G4 ; Hosseini M5 ; Shobeiri P6 ; Shafieioun A7 ; Khalafi M8 ; Shahidi R9 ; Sotoudeh H10 ; Singhal A11
Authors

Source: Radiology Case Reports Published:2023


Abstract

Anaplastic lymphoma kinase (ALK)-positive histiocytosis is an uncommon condition, recently considered a separate condition from other histiocytosis by WHO 5th edition. It can involve intracranial structures. This manuscript describes a case of ALK-positive histiocytosis of the cavernous sinus, focusing on the radiologic and pathologic presentation of the entity. Our case had MRI manifestations mimicking meningioma, metastasis, and Langerhans histiocytosis. On CT imaging, benign osseous remodeling of the cavernous sinus was detected, which can be helpful in differentiating it from more common meningioma. © 2023
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