Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Association Between Dietary Intakes of Nitrate and Nitrite With Angina and Atherogenic Index in Adults: A Cross-Sectional Study From Tehran University of Medical Sciences Employees` Cohort (Tec) Study Publisher Pubmed

Summary: Heart health via diet? Study finds high nitrate intake cuts angina odds by 29-46%—lowers atherogenic indices. #HeartHealth #Nutrition

Mirzababaei A1 ; Mahmoodi M2 ; Keshtkar A3 ; Ashraf H4 ; Abaj F1 ; Khosravinia D5 ; Radmehr M5 ; Rasaei N1 ; Mirzaei K1
Authors

Source: Current Problems in Cardiology Published:2024


Abstract

Background: Previous studies have shown that the intake of nitrate and nitrite may be associated with cardiovascular disease. Therefore, this study sought to investigate the association between dietary intakes of nitrate and nitrite with the odds of angina and atherogenic index in adults. Methods: The study analyzed 1182 adults aged 20+ in the Tehran University of Medical Sciences (TUMS) Employee's Cohort study (TEC), focusing on dietary intakes, angina, and atherogenic indexes, using a validated food frequency questionnaire (FFQ) and the Rose Angina Questionnaire (RAQ). Result: The study found a significant inverse relationship between nitrate intake and odds of grade 2 angina. The highest dietary nitrate was associated with 29 % lower odds of grade 1 angina and also, 46 % lower odds of angina possible (P<0.05). Adults with the highest nitrate intake had 29 % lower odds of grade 1 angina and 46 % lower odds of angina possible. Adherence to nitrate reduced CRI, Atherogenic index of plasma, and TyG in participants, but no significant association was found with other factors. Conclusion: The study suggests that high nitrate and nitrite intake can alter angina risk, and a reverse association was found between dietary nitrate intake and various atherogenic indices. © 2023
Related Docs
View other Related Docs
1. Plasma Nitrate, Dietary Nitrate, Blood Pressure, and Vascular Health Biomarkers: A Grade-Assessed Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials, Nutrition Journal (2025)
2. The Association of Dietary Nitrates/Nitrites Intake and the Gut Microbial Metabolite Trimethylamine N-Oxide and Kynurenine in Adults: A Population-Based Study, Frontiers in Nutrition (2024)
3. The Effects of Dietary Nitrate on Blood Pressure and Vascular Health: An Umbrella Review and Updated Meta-Analysis and Meta-Regression, Journal of Functional Foods (2024)
Experts (# of related papers)
View all Related Experts
Khadijeh Mirzaei (8)
Kurosh Djafarian (2)
Association Between Dietary Intakes of Nitrate and Nitrite With Angina and Atherogenic Index in Adults: A Cross-Sectional Study From Tehran University of Medical Sciences Employees` Cohort (Tec) Study
Other Related Docs
4. The Relationship Between Ultra-Processed Food Intake and Cardiometabolic Risk Factors in Overweight and Obese Women: A Cross-Sectional Study, Frontiers in Nutrition (2022)
5. The Association Between Adherence to Diet Quality Index and Cardiometabolic Risk Factors in Overweight and Obese Women: A Cross-Sectional Study, Frontiers in Public Health (2023)
6. Relationship Between Dietary Approaches to Stop Hypertension Score and Alternative Healthy Eating Index Score With Plasma Asymmetrical Dimethylarginine Levels in Patients Referring for Coronary Angiography, Journal of Human Nutrition and Dietetics (2015)
7. Ultra-Processed Foods and Coronary Artery Disease Severity: A Cross-Sectional Study of At-Risk Normal-Weight and Overweight Patients Undergoing Elective Angiography, Journal of Health, Population and Nutrition (2025)
8. Nitrate-Nitrite Exposure Through Drinking Water and Diet and Risk of Colorectal Cancer: A Systematic Review and Meta-Analysis of Observational Studies, Clinical Nutrition (2021)
9. The Association Between Dietary Nitrate, Nitrite and Total Antioxidant Capacity With Cardiometabolic Risk Factors: A Cross-Sectional Study Among Patients With Type 2 Diabetes, International Journal of Food Sciences and Nutrition (2024)
10. The Relationship Between Ultra Processed Food Consumption and Premature Coronary Artery Disease: Iran Premature Coronary Artery Disease Study (Ipad), Frontiers in Nutrition (2023)
11. The Association Between Recommended and Non-Recommended Food Scores on Cardiovascular Risk Factors in Obese and Overweight Adult Women: A Cross-Sectional Study, BMC Public Health (2022)
12. Serum Levels of Trimethylamine N-Oxide and Kynurenine Novel Biomarkers Are Associated With Adult Metabolic Syndrome and Its Components: A Case-Control Study From the Tec Cohort, Frontiers in Nutrition (2024)
13. The Effect of Dietary Total Antioxidant Capacity (Dtac) and Caveolin-1 Gene Variant Interaction on Cardiovascular Risk Factors Among Overweight and Obese Women: A Cross-Sectional Investigation, Clinical Nutrition (2021)
14. Association Between the Dash Diet and Metabolic Syndrome Components in Iranian Adults, Diabetes and Metabolic Syndrome: Clinical Research and Reviews (2019)
15. The Effects of Melissa Officinalis on Echocardiography, Exercise Test, Serum Biomarkers, and Blood Pressure in Patients With Chronic Stable Angina, Journal of Herbal Medicine (2018)
16. Coronary Artery Stenosis and Associations With Indicators of Anthropometric and Diet in Patients Undergoing Coronary Angiography, Journal of Diabetes and Metabolic Disorders (2018)
17. Association Between Adherence to the Mediterranean Diet and Renal Function Biomarkers and Cardiovascular Risk Factors Among Diabetic Patients With Nephropathy, Clinical Nutrition ESPEN (2020)
18. Dietary Protein Sources and Risk of Diabetic Nephropathy in Women: A Case-Control Study, BMC Endocrine Disorders (2021)
19. Association Between Consumption of Different Food Groups and Risk of Chronic Kidney Disease: A Dose-Response Meta-Analysis of Prospective Cohort Studies, British Journal of Nutrition (2025)
20. Investigation the Interaction of Dietary Fat Quality Indices and the Mc4r Gene in Metabolically Healthy and Unhealthy Overweight and Obese Women, Scientific Reports (2023)