Melatonin Could Be Beneficial in Sars-Cov-2 Therapy Publisher



Rahimi SB¹ ; Adli AH^{2, 3}
Source: Natural Products Journal Published:2021

Abstract

Novel coronavirus (SARS-CoV-2) can infect the respiratory tract and cause severe respiratory syndrome. The excessive inflammatory response is involved in the pathogenicity of the SARS-CoV-2. Symptoms of SARS-CoV-2 are generally associated with immunopathogenesis and may result in pulmonary tissue damage. Melatonin is a natural and multifunctional hormone that is involved in both physiological and pathological conditions in the body, such as immune modula-tion, anti-inflammation, and antioxidant. Melatonin is found in foods, animal and human milk and increases the expression of anti-inflammatory cytokines and, as an adjuvant treatment in SARS--CoV-2 infection, it may have considerable therapeutic potential, because of its safety and immuno-modulatory effects. © 2021 Bentham Science Publishers.