Biosensors; Nanomaterial-Based Methods in Diagnosing of Mycobacterium Tuberculosis Publisher



Mobed A¹ ; Darvishi M² ; Kohansal F³ ; Dehfooli FM⁴ ; Alipourfard I⁵ ; Tahavvori A⁶ ; Ghazi F⁶
Source: Journal of Clinical Tuberculosis and Other Mycobacterial Diseases Published:2024

Abstract

Diagnosis of Mycobacterium tuberculosis (Mtb) before the progression of pulmonary infection can be very effective in its early treatment. The Mtb grows so slowly that it takes about 6–8 weeks to be diagnosed even using sensitive cell culture methods. The main opponent in tuberculosis (TB) and nontuberculous mycobacterial (NTM) epidemiology, like in all contagious diseases, is to pinpoint the source of infection and reveal its transmission and dispersion ways in the environment. It is crucial to be able to distinguish and monitor specific mycobacterium strains in order to do this. In food analysis, clinical diagnosis, environmental monitoring, and bioprocess, biosensing technologies have been improved to manage and detect Mtb. Biosensors are progressively being considered pioneering tools for point-of-care diagnostics in Mtb discoveries. In this review, we present an epitome of recent developments of biosensing technologies for M. tuberculosis detection, which are categorized on the basis of types of electrochemical, Fluorescent, Photo-thermal, Lateral Flow, Magneto-resistive, Laser, Plasmonic, and Optic biosensors. © 2023 The Author(s)