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Molecular Evidence Reveals Thyrotropin Intervention Enhances the Risk of Developing Radioiodine-Refractory Differentiated Thyroid Carcinoma Publisher



Samimi H1 ; Haghpanah V1, 2
Authors

Source: Cancer Cell International Published:2022


Abstract

Radioiodine (RAI) is the mainstay of treatment for differentiated thyroid carcinoma (DTC) following total thyroidectomy. Nevertheless, about 5% of patients with DTC are RAI-refractory (RAI-R). Understanding the molecular mechanisms associated with DTC during progression towards RAI-R DTC, including thyroid-stimulating hormone levels, may help to explain the pathophysiology of challenging RAI-R DTC clinical cases. Graphical Abstract: [Figure not available: see fulltext.] © 2022, The Author(s).
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