Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
The Potential Use of Antibiotics Against Helicobacter Pylori Infection: Biopharmaceutical Implications Publisher



Miri AH1, 2 ; Kamankesh M3 ; Llopislorente A4 ; Liu C5 ; Wacker MG6 ; Haririan I1 ; Asadzadeh Aghdaei H7 ; Hamblin MR8 ; Yadegar A2 ; Radmalekshahi M1 ; Zali MR9
Authors

Source: Frontiers in Pharmacology Published:2022


Abstract

Helicobacter pylori (H. pylori) is a notorious, recalcitrant and silent germ, which can cause a variety of debilitating stomach diseases, including gastric and duodenal ulcers and gastric cancer. This microbe predominantly colonizes the mucosal layer of the human stomach and survives in the inhospitable gastric microenvironment, by adapting to this hostile milieu. In this review, we first discuss H. pylori colonization and invasion. Thereafter, we provide a survey of current curative options based on polypharmacy, looking at pharmacokinetics, pharmacodynamics and pharmaceutical microbiology concepts, in the battle against H. pylori infection. Copyright © 2022 Miri, Kamankesh, Llopis-Lorente, Liu, Wacker, Haririan, Asadzadeh Aghdaei, Hamblin, Yadegar, Rad-Malekshahi and Zali.
Other Related Docs
18. An Update on Eradication of Helicobacter Pylori in Iran: A Review, Middle East Journal of Digestive Diseases (2024)