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The Influence of Different Mode of Power Density During Antimicrobial Photodynamic Therapy for Photokilling of Streptococcus Mutans Publisher Pubmed



Afrasiabi S1 ; Entezari S2 ; Etemadi A3 ; Chiniforush N1
Authors

Source: Photodiagnosis and Photodynamic Therapy Published:2023


Abstract

Background: The aim of this study was to evaluate the inactivation potency of riboflavin and curcumin plus blue diode laser against Streptococcus mutans with different power densities. Materials and methods: In this in vitro study, standard-strain S. mutans was exposed to curcumin and riboflavin plus blue diode laser with different power densities (0.4–1.0 W/cm2) as well as chlorhexidine (CHX). The colony forming units (CFUs)/mL was calculated. Data were analyzed by one-way ANOVA. Results: Antibacterial analysis indicated that the blue diode laser irradiation with curcumin and riboflavin provided a satisfactory reduction of the S. mutans level. In addition, S. mutans was more affected by curcumin + blue diode laser when the power density was set to 1.0 W/cm2 (P < 0.0001). Meanwhile, bacterial suspensions treated with CHX showed maximum colony number reduction, compared with the control (P < 0.0001). Conclusion: This study showed the blue diode laser along with curcumin had strong bactericidal effect on S. mutans, and this effect improved by increasing the power density. © 2023 Elsevier B.V.
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