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Potential Roles of Endothelial Cells-Related Non-Coding Rnas in Cardiovascular Diseases Publisher Pubmed



Azizidoost S1 ; Nasrolahi A2 ; Sheykhisabzehpoush M3 ; Akiash N1 ; Assareh AR1 ; Anbiyaee O4 ; Antosik P5 ; Dziegiel P6 ; Farzaneh M7 ; Kempisty B5, 8, 9
Authors

Source: Pathology Research and Practice Published:2023


Abstract

Endothelial dysfunction is identified by a conversion of the endothelium toward decreased vasodilation and prothrombic features and is known as a primary pathogenic incident in cardiovascular diseases. An insight based on particular and promising biomarkers of endothelial dysfunction may possess vital clinical significances. Currently, non-coding RNAs due to their participation in critical cardiovascular processes like initiation and progression have gained much attention as possible diagnostic as well as prognostic biomarkers in cardiovascular diseases. Emerging line of proof has demonstrated that abnormal expression of non-coding RNAs is nearly correlated with the pathogenesis of cardiovascular diseases. In the present review, we focus on the expression and functional effects of various kinds of non-coding RNAs in cardiovascular diseases and negotiate their possible clinical implications as diagnostic or prognostic biomarkers and curative targets. © 2023
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