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Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1



Bahrami A1 ; Sadeghian M2 ; Sheikhvatan M3 ; Foroudi A1 ; Harsini S4, 5 ; Rezaei N4, 5, 6
Authors

Source: Acta Medica Iranica Published:2018

Abstract

Leukocyte adhesion deficiency type 1 (LAD-1) is a rare autosomal recessive immunodeficiency disorder, characterized by recurrent bacterial and fungal infections without pus formation. Herein, we report a case of LAD-1 that developed into gastrointestinal cytomegalovirus (CMV) disease and manifested with persistent abdominal pain and bloody diarrhea. Although the presence of concurrent gastrointestinal CMV infection with LAD-1 is a rare condition, this case highlights the need for further research to evaluate the complex mechanisms between LAD-1 and CMV occurrence. © 2018 Tehran University of Medical Sciences. All rights reserved.