In Vitro Anti-Toxoplasma Gondii Activity of Ganoderma Lucidum Extracts

In Vitro Anti-Toxoplasma Gondii Activity of Ganoderma Lucidum Extracts Publisher Pubmed

Ahmadi M¹ ; Salimi M² ; Saraei M^{3, 4} ; Nezhad NS⁵ ; Javadi A⁶ ; Mohammadi F^{3, 4} ; Heydarian P^{3, 4} ; Ali E⁷ ; Hajialilo E^{3, 4}

Source: BMC Research Notes Published:2023

Abstract

Objective: Ganoderma extracts have the potential to be used as anti-cancer, anti-inflammatory, immunomodulator, and antimicrobial agents, as evaluated in numerous studies. This study was aimed to determine the lethal and inhibitory effects of aqueous, hydroalcoholic, and alcoholic extracts of Ganoderma lucidum on Toxoplasma gondii RH strain tachyzoites, in vitro. Results: All three types of extracts showed toxoplasmacidal effects. The highest percentage of mortality was related to hydroalcoholic extract. The EC50 of Ganoderma extracts for tachyzoites were 76.32, 3.274, and 40.18 for aqueous, hydroalcoholic and alcoholic extracts, respectively. The selectivity index obtained for hydroalcoholic extract was 71.22, showing the highest activity compared to other extracts. According to our findings, the hydroalcoholic part was the most effective substance among the extracts. This basic study showed obvious anti-toxoplasma effect of Ganoderma lucidum extracts. These extracts can be used as candidates for further in-depth and comprehensive studies especially In vivo experiments to prevent toxoplasmosis. © 2023, The Author(s).

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Style	Citing Format
MLA	Ahmadi M, et al.. "In Vitro Anti-Toxoplasma Gondii Activity of Ganoderma Lucidum Extracts." BMC Research Notes, vol. 16, no. 1, 2023, pp. -.
APA	Ahmadi M, Salimi M, Saraei M, Nezhad NS, Javadi A, Mohammadi F, Heydarian P, Ali E, Hajialilo E (2023). In Vitro Anti-Toxoplasma Gondii Activity of Ganoderma Lucidum Extracts. BMC Research Notes, 16(1), -.
Chicago	Ahmadi M, Salimi M, Saraei M, Nezhad NS, Javadi A, Mohammadi F, Heydarian P, Ali E, Hajialilo E. "In Vitro Anti-Toxoplasma Gondii Activity of Ganoderma Lucidum Extracts." BMC Research Notes 16, no. 1 (2023): -.
Harvard	Ahmadi M et al. (2023) 'In Vitro Anti-Toxoplasma Gondii Activity of Ganoderma Lucidum Extracts', BMC Research Notes, 16(1), pp. -.
Vancouver	Ahmadi M, Salimi M, Saraei M, Nezhad NS, Javadi A, Mohammadi F, et al.. In Vitro Anti-Toxoplasma Gondii Activity of Ganoderma Lucidum Extracts. BMC Research Notes. 2023;16(1):-.
BibTex	@article{ author = {Ahmadi M and Salimi M and Saraei M and Nezhad NS and Javadi A and Mohammadi F and Heydarian P and Ali E and Hajialilo E}, title = {In Vitro Anti-Toxoplasma Gondii Activity of Ganoderma Lucidum Extracts}, journal = {BMC Research Notes}, volume = {16}, number = {1}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Ahmadi M AU - Salimi M AU - Saraei M AU - Nezhad NS AU - Javadi A AU - Mohammadi F AU - Heydarian P AU - Ali E AU - Hajialilo E TI - In Vitro Anti-Toxoplasma Gondii Activity of Ganoderma Lucidum Extracts JO - BMC Research Notes VL - 16 IS - 1 SP - EP - PY - 2023 ER -

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