Perspective of Placenta Derived Mesenchymal Stem Cells in Acute Liver Failure

Perspective of Placenta Derived Mesenchymal Stem Cells in Acute Liver Failure Publisher

Saleh M¹ ; Taher M² ; Sohrabpour AA³ ; Vaezi AA⁴ ; Nasiri Toosi M⁵ ; Kavianpour M¹ ; Ghazvinian Z¹ ; Abdolahi S¹ ; Verdi J¹

Source: Cell and Bioscience Published:2020

Abstract

Acute Liver failure (ALF) is a life-threatening disease and is determined by coagulopathy (with INR ≥ 1.5) and hepatic encephalopathy as a result of severe liver injury in patients without preexisting liver disease. Since there are problems with liver transplantation including lack of donors, use of immunosuppressive drugs, and high costs of this process, new therapeutic approaches alongside current treatments are needed. The placenta is a tissue that is normally discarded after childbirth. On the other hand, human placenta is a rich source of mesenchymal stem cells (MSCs), which is easily available, without moral problems, and its derived cells are less affected by age and environmental factors. Therefore, placenta-derived mesenchymal stem cells (PD-MSCs) can be considered as an allogeneic source for liver disease. Considering the studies on MSCs and their effects on various diseases, it can be stated that MSCs are among the most important agents to be used for novel future therapies of liver diseases. In this paper, we will investigate the effects of mesenchymal stem cells through migration and immigration to the site of injury, cell-to-cell contact, immunomodulatory effects, and secretory factors in ALF. © 2020 The Author(s).

Related Docs

View other Related Docs

1. Bone Tissue Engineering Using Human Cells: A Comprehensive Review on Recent Trends, Current Prospects, and Recommendations, Applied Sciences (Switzerland) (2019)

2. Application of Wharton Jelly-Derived Mesenchymal Stem Cells in Patients With Pulmonary Fibrosis, Stem Cell Research and Therapy (2022)

3. Biological Aspects and Clinical Applications of Mesenchymal Stem Cells: Key Features You Need to Be Aware Of, Current Pharmaceutical Biotechnology (2021)

Experts (# of related papers)

View all Related Experts

Seyed Asadollah Mousavi (3)

Mohsen Nikbakht (3)

Style	Citing Format
MLA	Saleh M, et al.. "Perspective of Placenta Derived Mesenchymal Stem Cells in Acute Liver Failure." Cell and Bioscience, vol. 10, no. 1, 2020, pp. -.
APA	Saleh M, Taher M, Sohrabpour AA, Vaezi AA, Nasiri Toosi M, Kavianpour M, Ghazvinian Z, Abdolahi S, Verdi J (2020). Perspective of Placenta Derived Mesenchymal Stem Cells in Acute Liver Failure. Cell and Bioscience, 10(1), -.
Chicago	Saleh M, Taher M, Sohrabpour AA, Vaezi AA, Nasiri Toosi M, Kavianpour M, Ghazvinian Z, Abdolahi S, Verdi J. "Perspective of Placenta Derived Mesenchymal Stem Cells in Acute Liver Failure." Cell and Bioscience 10, no. 1 (2020): -.
Harvard	Saleh M et al. (2020) 'Perspective of Placenta Derived Mesenchymal Stem Cells in Acute Liver Failure', Cell and Bioscience, 10(1), pp. -.
Vancouver	Saleh M, Taher M, Sohrabpour AA, Vaezi AA, Nasiri Toosi M, Kavianpour M, et al.. Perspective of Placenta Derived Mesenchymal Stem Cells in Acute Liver Failure. Cell and Bioscience. 2020;10(1):-.
BibTex	@article{ author = {Saleh M and Taher M and Sohrabpour AA and Vaezi AA and Nasiri Toosi M and Kavianpour M and Ghazvinian Z and Abdolahi S and Verdi J}, title = {Perspective of Placenta Derived Mesenchymal Stem Cells in Acute Liver Failure}, journal = {Cell and Bioscience}, volume = {10}, number = {1}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Saleh M AU - Taher M AU - Sohrabpour AA AU - Vaezi AA AU - Nasiri Toosi M AU - Kavianpour M AU - Ghazvinian Z AU - Abdolahi S AU - Verdi J TI - Perspective of Placenta Derived Mesenchymal Stem Cells in Acute Liver Failure JO - Cell and Bioscience VL - 10 IS - 1 SP - EP - PY - 2020 ER -

Science Communicator Platform

Authors

Abstract