Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder

Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder Publisher Pubmed

Mohammadzadeh Honarvar N¹ ; Samadi M¹ ; Seyedi Chimeh M¹ ; Gholami F¹ ; Bahrampour N² ; Jalali M¹ ; Effatpanah M³ ; Yekaninejad MS⁴ ; Abdolahi M¹ ; Chamari M¹

Source: International journal of clinical practice Published:2022

Abstract

Method: In this double-blind, randomized, placebo-controlled trial, 75 children (aged 6-12) diagnosed with ADHD were randomly assigned into two groups. The supplementation group received vitamin D3 (2000 IU), and the control group received a placebo for 3 months. Blood samples were collected at baseline and after intervention to analyze the 25(OH)D, paraxonase-1 activity (PON-1), Total Antioxidant Capacity (TAC), and 8-isoprostan levels. Results: A significant rise in circulating 25(OH)D was observed in the vitamin D group versus the placebo group at the end of the study. There was no reduction in 8-isoprostan levels in the vitamin D group compared to the placebo group. Serum paraxonase-1 and TAC concentration decreased in both groups, but these alterations were not statistically significant in the treatment group versus the placebo group at the end of the intervention. Conclusion: Vitamin D supplementation for 3 months did not have beneficial effects on biomarkers of oxidative stress status. To confirm these findings, further studies on children are suggested. Copyright © 2022 Niyaz Mohammadzadeh Honarvar et al.

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Style	Citing Format
MLA	Mohammadzadeh Honarvar N, et al.. "Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder." International journal of clinical practice, vol. 2022, no. , 2022, pp. 4836731-.
APA	Mohammadzadeh Honarvar N, Samadi M, Seyedi Chimeh M, Gholami F, Bahrampour N, Jalali M, Effatpanah M, Yekaninejad MS, Abdolahi M, Chamari M (2022). Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder. International journal of clinical practice, 2022(), 4836731-.
Chicago	Mohammadzadeh Honarvar N, Samadi M, Seyedi Chimeh M, Gholami F, Bahrampour N, Jalali M, Effatpanah M, Yekaninejad MS, Abdolahi M, Chamari M. "Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder." International journal of clinical practice 2022, no. (2022): 4836731-.
Harvard	Mohammadzadeh Honarvar N et al. (2022) 'Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder', International journal of clinical practice, 2022(), pp. 4836731-.
Vancouver	Mohammadzadeh Honarvar N, Samadi M, Seyedi Chimeh M, Gholami F, Bahrampour N, Jalali M, et al.. Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder. International journal of clinical practice. 2022;2022():4836731-.
BibTex	@article{ author = {Mohammadzadeh Honarvar N and Samadi M and Seyedi Chimeh M and Gholami F and Bahrampour N and Jalali M and Effatpanah M and Yekaninejad MS and Abdolahi M and Chamari M}, title = {Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder}, journal = {International journal of clinical practice}, volume = {2022}, number = {}, pages = {4836731-}, year = {2022} }
RIS	TY - JOUR AU - Mohammadzadeh Honarvar N AU - Samadi M AU - Seyedi Chimeh M AU - Gholami F AU - Bahrampour N AU - Jalali M AU - Effatpanah M AU - Yekaninejad MS AU - Abdolahi M AU - Chamari M TI - Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder JO - International journal of clinical practice VL - 2022 IS - SP - 4836731 EP - PY - 2022 ER -

Style

Citing Format

MLA

Mohammadzadeh Honarvar N, et al.. "Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder." International journal of clinical practice, vol. 2022, no. , 2022, pp. 4836731-.

APA

Mohammadzadeh Honarvar N, Samadi M, Seyedi Chimeh M, Gholami F, Bahrampour N, Jalali M, Effatpanah M, Yekaninejad MS, Abdolahi M, Chamari M (2022). Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder. International journal of clinical practice, 2022(), 4836731-.

Chicago

Mohammadzadeh Honarvar N, Samadi M, Seyedi Chimeh M, Gholami F, Bahrampour N, Jalali M, Effatpanah M, Yekaninejad MS, Abdolahi M, Chamari M. "Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder." International journal of clinical practice 2022, no. (2022): 4836731-.

Harvard

Mohammadzadeh Honarvar N et al. (2022) 'Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder', International journal of clinical practice, 2022(), pp. 4836731-.

Vancouver

Mohammadzadeh Honarvar N, Samadi M, Seyedi Chimeh M, Gholami F, Bahrampour N, Jalali M, et al.. Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder. International journal of clinical practice. 2022;2022():4836731-.

BibTex

@article{ author = {Mohammadzadeh Honarvar N and Samadi M and Seyedi Chimeh M and Gholami F and Bahrampour N and Jalali M and Effatpanah M and Yekaninejad MS and Abdolahi M and Chamari M}, title = {Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder}, journal = {International journal of clinical practice}, volume = {2022}, number = {}, pages = {4836731-}, year = {2022} }

RIS

TY - JOUR
AU - Mohammadzadeh Honarvar N
AU - Samadi M
AU - Seyedi Chimeh M
AU - Gholami F
AU - Bahrampour N
AU - Jalali M
AU - Effatpanah M
AU - Yekaninejad MS
AU - Abdolahi M
AU - Chamari M
TI - Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder
JO - International journal of clinical practice
VL - 2022
IS -
SP - 4836731
EP -
PY - 2022
ER -

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Abstract