Effect of Vitamin D Supplementation on Thioredoxin Binding Protein 2 Gene Expression in Patients With Diabetes Type 2

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Effect of Vitamin D Supplementation on Thioredoxin Binding Protein 2 Gene Expression in Patients With Diabetes Type 2

Rad EY¹ ; Attar MJH² ; Koohdani F¹ ; Sabooryaraghi AA¹ ; Eshraghian MR³ ; Javanbakht MH¹ ; Saboori S¹ ; Chamari M¹ ; And MZ¹ ; Djalali M¹

Source: Current Topics in Nutraceutical Research Published:2015

Abstract

Diabetes type 2 is an oxidative stress related disease. This randomized controlled trial was done to evaluate the effect of vitamin D supplementation on thioredoxin binding protein 2 (TBP-2) gene expression in patients with type 2 diabetes. Subjects of this study consist of 28 patients with type 2 diabetes who received 100μg (4000IU) vitamin D and 30 diabetic patients who received placebo for two months. The effect of vitamin D on gene expression of TBP-2 in PBMC cells was measured by RT-PCR at the beginning and at the end of the study. The results of this study showed no significant differences in TBP-2 gene expression between 2 groups, but a significant decrease in serum TBP-2 concentration in vitamin D receiving group at the end of supplementation. It seems that vitamin D supplementation has no effect on the TBP-2 gene expression in PBMC cells.

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Style	Citing Format
MLA	Rad EY, et al.. "Effect of Vitamin D Supplementation on Thioredoxin Binding Protein 2 Gene Expression in Patients With Diabetes Type 2." Current Topics in Nutraceutical Research, vol. 13, no. 1, 2015, pp. 55-60.
APA	Rad EY, Attar MJH, Koohdani F, Sabooryaraghi AA, Eshraghian MR, Javanbakht MH, Saboori S, Chamari M, And MZ, Djalali M (2015). Effect of Vitamin D Supplementation on Thioredoxin Binding Protein 2 Gene Expression in Patients With Diabetes Type 2. Current Topics in Nutraceutical Research, 13(1), 55-60.
Chicago	Rad EY, Attar MJH, Koohdani F, Sabooryaraghi AA, Eshraghian MR, Javanbakht MH, Saboori S, Chamari M, And MZ, Djalali M. "Effect of Vitamin D Supplementation on Thioredoxin Binding Protein 2 Gene Expression in Patients With Diabetes Type 2." Current Topics in Nutraceutical Research 13, no. 1 (2015): 55-60.
Harvard	Rad EY et al. (2015) 'Effect of Vitamin D Supplementation on Thioredoxin Binding Protein 2 Gene Expression in Patients With Diabetes Type 2', Current Topics in Nutraceutical Research, 13(1), pp. 55-60.
Vancouver	Rad EY, Attar MJH, Koohdani F, Sabooryaraghi AA, Eshraghian MR, Javanbakht MH, et al.. Effect of Vitamin D Supplementation on Thioredoxin Binding Protein 2 Gene Expression in Patients With Diabetes Type 2. Current Topics in Nutraceutical Research. 2015;13(1):55-60.
BibTex	@article{ author = {Rad EY and Attar MJH and Koohdani F and Sabooryaraghi AA and Eshraghian MR and Javanbakht MH and Saboori S and Chamari M and And MZ and Djalali M}, title = {Effect of Vitamin D Supplementation on Thioredoxin Binding Protein 2 Gene Expression in Patients With Diabetes Type 2}, journal = {Current Topics in Nutraceutical Research}, volume = {13}, number = {1}, pages = {55-60}, year = {2015} }
RIS	TY - JOUR AU - Rad EY AU - Attar MJH AU - Koohdani F AU - Sabooryaraghi AA AU - Eshraghian MR AU - Javanbakht MH AU - Saboori S AU - Chamari M AU - And MZ AU - Djalali M TI - Effect of Vitamin D Supplementation on Thioredoxin Binding Protein 2 Gene Expression in Patients With Diabetes Type 2 JO - Current Topics in Nutraceutical Research VL - 13 IS - 1 SP - 55 EP - 60 PY - 2015 ER -

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