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The Resistance to Plague Infection Among Meriones Persicus From Endemic and Non-Endemic Regions in Iran: The Role of Gut Microbiota



Assmar M1 ; Keypour M2, 3 ; Rohani M3, 4 ; Mostafavi E2, 3 ; Daneshvar Farhud D5, 6
Authors

Source: Iranian Journal of Public Health Published:2018

Abstract

Background: The present study was conducted approximately 40 years ago, but its results have not been re-leased. At the time of this study, the importance of the gut microbiota was not fully understood. Methods: Meriones persicus rodents, as one of the major reservoirs of Yersinia pestis bacterium in Iran, were compared in a disease endemic area (Akanlu, Hamadan, western Iran) and a non-endemic zone (Telo, Teh-ran, Iran) from 1977 to1981. Results: This study was able to transmit the resistance to Y. pestis to other rodents creatively by using and transferring gut microbiota. Conclusion: The study indicated for the first time that the gut microbiota could affect the sensitivity to plague in Meriones in Telo. © 2018, Iranian Journal of Public Health. All rights reserved.
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