Cardiogenetics: Genetics for Cardiologists Publisher



Rabbani B¹ ; Esmaeili S¹ ; Akbari B^{2, 3} ; Mahdieh N^{1, 4}
Source: Journal of Knowledge and Health in Basic Medical Sciences Published:2022

Abstract

Cardiovascular disease (CVD) is the leading cause of death worldwide, accounting for more than 17.9 million deaths a year. Various factors are involved in the disease's development, including lifestyle, nutrition, environment, and genetic factors. Genetics is one of the main causes of CVD because of the familial accumulation of these diseases especially in countries with traditional cultures. As a result, cardiologists need to be aware of the genetic background of CVD and how to use genetic testing to diagnose and find therapeutic solutions. Here, the genetic basis of various CVDs, especially those with single-gene inheritance, diagnostic methods, and advanced genetic diagnostic techniques are reviewed. Also, for each disease, candidate genes, and molecular genetic techniques appropriately to diagnose are suggested and introduced. © 2022, Shahroud University of Medical Sciences. All rights reserved.