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The Regenerative Potential of Glial Progenitor Cells and Reactive Astrocytes in Cns Injuries Publisher Pubmed



Kiaie N1 ; Gorabi AM2 ; Loveless R3 ; Teng Y4 ; Jamialahmadi T5, 6 ; Sahebkar A5, 7, 8
Authors

Source: Neuroscience and Biobehavioral Reviews Published:2022


Abstract

Cell therapeutic approaches focusing on the regeneration of damaged tissue have been a popular topic among researchers in recent years. In particular, self-repair scarring from the central nervous system (CNS) can significantly complicate the treatment of an injured patient. In CNS regeneration schemes, either glial progenitor cells or reactive glial cells have key roles to play. In this review, the contribution and underlying mechanisms of these progenitor/reactive glial cells during CNS regeneration are discussed, as well as their role in CNS-related diseases. © 2022 Elsevier Ltd
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