The Immunoemotional Regulatory System Publisher



Saghazadeh A^{1, 2} ; Rezaei N^{3, 4, 5}
Source: Biophysics and Neurophysiology of the Sixth Sense Published:2019

Abstract

The present chapter provides a digest of data for the compartments of the immunoemotional regulatory system including cytokines, mast cells, lymphocytes, natural killer cells, antibodies and immunoglobulins, toll-like receptors, lipopolysaccharide-binding protein, oxidative stress, microglia cells, NF-κB pathway, hypothalamic-pituitary-adrenal (HPA) axis, neuronal circuits, and blood-brain barrier (BBB). The chapter highlights that the immunoemotional regulatory system (a) fits both of the chronic emotion dysregulation (EDR)-related disorders/conditions and (b) rests on both the immune and non-immune compartments and their functional relationship. Findings highlight the importance of considering psychological status in the immunological studies and warrant further investigations to determine the extent by which manipulating the immune response/emotion regulation (ER) is effective at managing EDR/immune-related disorders. © Springer Nature Switzerland AG 2019.