Lncrna Pvt1-Mediated Regulation of Cardiovascular Diseases: A New Paradigm

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Summary: Could the RNA PVT1 help explain heart disease? A review explores its roles in inflammation and cell signaling, but its clinical biomarker and treatment value remains uncertain. #lncRNA #Cardiology

Haybar H ; Shooshtari M K ; Ghaedrahmati F ; Khavanin A ; Mohammadzadeh M ; Haybar M ; Azizidoost S ; Farzaneh M

Source: Current Molecular Medicine Published:2026

Abstract

A notable mortality rate is related to cardiovascular disorders despite progress in therapy. Long non-coding RNAs (lncRNAs) play pivotal roles in diverse biological processes, and the abnormal regulation of their downstream signals is linked to a broad range of disorders. A lncRNA, Plasmacytoma Variant Translocation 1 (PVT1), has been found to be associated with the pathogenesis of human diseases. According to recent studies, lncRNA PVT1 participates in a variety of cellular processes, including proliferation, migration, and inflammation, via molecular axes with microRNAs and their downstream targets in neoplastic and non-neoplastic disorders. Given the involvement of these cellular processes in the pathogenesis of cardiovascular disease, we aim to clarify the function of the lncRNA PVT1 in this process. In addition, we aim to determine whether it is a prognostic factor or a potential therapeutic target in cardiovascular disorders. 2026, Bentham Science Publishers

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Style	Citing Format
MLA	Haybar H, et al.. "Lncrna Pvt1-Mediated Regulation of Cardiovascular Diseases: A New Paradigm." Current Molecular Medicine, vol. , no. , 2026, pp. -.
APA	Haybar H, Shooshtari M K, Ghaedrahmati F, Khavanin A, Mohammadzadeh M, Haybar M, Azizidoost S, Farzaneh M (2026). Lncrna Pvt1-Mediated Regulation of Cardiovascular Diseases: A New Paradigm. Current Molecular Medicine, (), -.
Chicago	Haybar H, Shooshtari M K, Ghaedrahmati F, Khavanin A, Mohammadzadeh M, Haybar M, Azizidoost S, Farzaneh M. "Lncrna Pvt1-Mediated Regulation of Cardiovascular Diseases: A New Paradigm." Current Molecular Medicine , no. (2026): -.
Harvard	Haybar H et al. (2026) 'Lncrna Pvt1-Mediated Regulation of Cardiovascular Diseases: A New Paradigm', Current Molecular Medicine, (), pp. -.
Vancouver	Haybar H, Shooshtari M K, Ghaedrahmati F, Khavanin A, Mohammadzadeh M, Haybar M, et al.. Lncrna Pvt1-Mediated Regulation of Cardiovascular Diseases: A New Paradigm. Current Molecular Medicine. 2026;():-.
BibTex	@article{ author = {Haybar H and Shooshtari M K and Ghaedrahmati F and Khavanin A and Mohammadzadeh M and Haybar M and Azizidoost S and Farzaneh M}, title = {Lncrna Pvt1-Mediated Regulation of Cardiovascular Diseases: A New Paradigm}, journal = {Current Molecular Medicine}, volume = {}, number = {}, pages = {-}, year = {2026} }
RIS	TY - JOUR AU - Haybar H AU - Shooshtari M K AU - Ghaedrahmati F AU - Khavanin A AU - Mohammadzadeh M AU - Haybar M AU - Azizidoost S AU - Farzaneh M TI - Lncrna Pvt1-Mediated Regulation of Cardiovascular Diseases: A New Paradigm JO - Current Molecular Medicine VL - IS - SP - EP - PY - 2026 ER -

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