Determining the Diagnostic Value of Dwibs in the Diagnosis of Breast Lesions Compared to Dynamic Contrast‑Enhanced Mri: A Retrospective Observational Study Publisher



Farghadani M¹ ; Mozafari S² ; Riahinejad M¹ ; Haghighi M¹ ; Samani RE³ ; Taravati AM⁴ ; Rostami K⁵ ; Shahrokh SG⁴ ; Sadeghian A¹
Source: Advanced Biomedical Research Published:2025

Abstract

Background: Diffusion‑weighted imaging with background body signal suppression (DWIBS) is a new imaging tool for the diagnosis of breast lesions. This study aims to compare DWIBS with contrast‑enhanced magnetic resonance imaging (CE‑MRI) sequences. Materials and Methods: Eighty consecutive patients underwent both CE‑MRI and DWIBS images. DWIBS was assessed qualitatively and quantitatively using the apparent diffusion coefficient mapping. A threshold of 1.44 × 10‑3 mm2/s was considered as a cutoff value between malignant and benign lesions. CE‑MRI images were evaluated based on a combination of kinetic and morphological information and reported using Breast Imaging Reporting and Data System lexicon. Statistical analysis was performed for both sequences based on pathologic findings as a gold standard. Results: Fifty‑five out of 80 lesions (69%) were benign, and 25 malignant lesions (31%) have been reported. The sensitivity, specificity, positive predictive value, and negative predictive value for CE‑MRI were 100, 38, 42, and 100%, respectively, and those for DWIBS were 77, 70, 53, and 87%, respectively. By comparing DWIBS and CE‑MRI data, no statistically significant difference was reported. Conclusion: DWIBS can be used as an effective alternative for breast CE‑MRI in cases of contradictions of IV contrast injection. © 2025 Advanced Biomedical Research | Published by Wolters Kluwer - Medknow.