Isfahan University of Medical Sciences

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Soft Tissue Augmentation by Autologous Cultured Fibroblasts Transplantation for Treatment of Wrinkles and Scars: A Case Series of 20 Patients



Nilforoushzadeh MA1 ; Siadat AH2 ; Arianrad M3 ; Moulavi F4, 5 ; Haftbaradaran E3 ; Esfahani MHN4, 5
Authors

Source: Journal of Research in Medical Sciences Published:2010

Abstract

BACKGROUND: There are many filler agents for augmentation of static wrinkles and atrophic scars from synthetic, biosynthetic, cadaver, animal and human sources. METHODS: The current study presents 20 patients whose facial wrinkles and lines were treated by transplantation of autologous cultured fibroblasts. The fibroblast nature of cells was confirmed by immune-staining and flow cytometry. RESULTS: The mean of improvement for this procedure at the 6 month follow up was 41%. CONCLUSIONS: In conclusion autologous fibroblast transplantation can be an effective procedure for correction of wrinkles and atrophic scars.