Gastrointestinal Cancers Publisher



Tabatabaiefar MA¹ ; Moridnia A²
Source: Cancer Genetics and Psychotherapy Published:2017

Abstract

Gastrointestinal cancers (GI) are an important category of cancers. This chapter reviews the updates on different aspects of GI cancers including pathophysiology, classification, genetics, genotype-phenotype correlations, screening, surveillance, genetic counseling, testing strategies, management and individualized medicine of esophageal cancers (squamous cell carcinoma and adenocarcinoma), gastric cancer (intestinal and diffuse subtypes), and colorectal cancers (CRCs) (with focus on Lynch syndrome and adenomatous polyposis colon cancer which are two common hereditary form of CRCs). Our current understanding of different aspects of GI cancers and future directions especially in the issues of genetic profiling and targeted therapies in GI cancers are tried to be address in this chapter. © Springer International Publishing AG 2017. All rights reserved.