Mir-1236: Key Controller of Tumor Development and Progression: Focus on the Biological Functions and Molecular Mechanisms

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):

Share By

Mir-1236: Key Controller of Tumor Development and Progression: Focus on the Biological Functions and Molecular Mechanisms Publisher Pubmed

Babaei Z¹ ; Keyvanloo Shahrestanaki M² ; Aghaei M³

Source: Pathology Research and Practice Published:2023

Abstract

Combating with the cancer, as one of the leading causes of morbidity and mortality worldwide, scientific community extensively evidenced microRNA 1236 (miR-1236) roles in the pathogenesis of malignant tumors. It has been mentioned that miR-1236 target genes and signal pathways that are key controller of tumor development and progression. Consistently, increasing evidence reports that miR-1236 participates in cancer cell growth, migration, invasion, apoptosis, and drug resistance, as well as tumor diagnosis, and prognosis. MiR-1236 is also implicated in epithelial–mesenchymal transition (EMT), which is a significant indicator of the metastatic process. Moreover, miR-1236 itself is regulated by several newly discovered long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs). Current review aimed to summarize and discuss different dimensions of miR-1236 involvement in the fundamental cellular and molecular mechanisms of tumor progressions. We believe that miR-1236 may serve as a non-invasive diagnostic marker and potential therapeutic target for cancer. © 2023 Elsevier GmbH

Related Docs

View other Related Docs

1. Vegfr3 Suppression Through Mir-1236 Inhibits Proliferation and Induces Apoptosis in Ovarian Cancer Via Erk1/2 and Akt Signaling Pathways, Journal of Cellular Biochemistry (2023)

2. Molecular Mechanisms of Mir-1236 in the Assessment of Tumor Lymphangiogenesis in Human Ovarian Cancer Patients, Journal of Gene Medicine (2023)

3. The Regulatory Role of Circular Rnas As Mirna Sponges in Cervical Cancer, Current Signal Transduction Therapy (2023)

Experts (# of related papers)

View all Related Experts

Mahmoud Aghaei (3)

Hamed Fooladseresht (2)

Other Related Docs

4. Circular Rnas-Mediated Angiogenesis in Human Cancers, Clinical and Translational Oncology (2023)

5. Micrornas, Long Non-Coding Rnas, and Circular Rnas and Gynecological Cancers: Focus on Metastasis, Frontiers in Oncology (2023)

6. Dysregulated Expression and Functions of Microrna-330 in Cancers: A Potential Therapeutic Target, Biomedicine and Pharmacotherapy (2022)

7. Microrna-184 in the Landscape of Human Malignancies: A Review to Roles and Clinical Significance, Cell Death Discovery (2023)

8. Sar131675 Exhibits Anticancer Activity on Human Ovarian Cancer Cells Through Inhibition of Vegfr-3/Erk1/2/Akt Signaling Pathway, Cellular Signalling (2023)

9. Inducer Micrornas in the Glioma Development: A Concise Review of Mechanisms and Insights Into Targeted Therapy, Journal of the Egyptian National Cancer Institute (2025)

10. A Review on Expression and Regulatory Mechanisms of Mir-337-3P in Cancer, Journal of Biomolecular Structure and Dynamics (2024)

11. Deciphering the Multifaceted Role of Micrornas in Hepatocellular Carcinoma: Integrating Literature Review and Bioinformatics Analysis for Therapeutic Insights, Heliyon (2024)

12. Emerging Biologic and Clinical Implications of Mir-182-5P in Gynecologic Cancers, Clinical and Translational Oncology (2024)

13. Mir-196: Emerging of a New Potential Therapeutic Target and Biomarker in Colorectal Cancer, Molecular Biology Reports (2020)

14. The Prominent Role of Mir-942 in Carcinogenesis of Tumors, Advanced Biomedical Research (2022)

15. A Spotlight on the Interplay Between Wnt/Β-Catenin Signaling and Circular Rnas in Hepatocellular Carcinoma Progression, Frontiers in Oncology (2023)

16. Mir-939, As an Important Regulator in Various Cancers Pathogenesis, Has Diagnostic, Prognostic, and Therapeutic Values: A Review, Journal of the Egyptian National Cancer Institute (2024)

17. The Importance of the Circrna/Wnt Axis in Gliomas: Biological Functions and Clinical Opportunities, Pathology Research and Practice (2024)

18. Epi-Drugs and Epi-Mirs: Moving Beyond Current Cancer Therapies, Current Cancer Drug Targets (2016)

19. Circular Rnas: New Players in Thyroid Cancer, Pathology Research and Practice (2020)

20. The Pathogenic Roles of Lncrna-Taurine Upregulated 1 (Tug1) in Colorectal Cancer, Cancer Cell International (2022)

Style	Citing Format
MLA	Babaei Z, Keyvanloo Shahrestanaki M, Aghaei M. "Mir-1236: Key Controller of Tumor Development and Progression: Focus on the Biological Functions and Molecular Mechanisms." Pathology Research and Practice, vol. 248, no. , 2023, pp. -.
APA	Babaei Z, Keyvanloo Shahrestanaki M, Aghaei M (2023). Mir-1236: Key Controller of Tumor Development and Progression: Focus on the Biological Functions and Molecular Mechanisms. Pathology Research and Practice, 248(), -.
Chicago	Babaei Z, Keyvanloo Shahrestanaki M, Aghaei M. "Mir-1236: Key Controller of Tumor Development and Progression: Focus on the Biological Functions and Molecular Mechanisms." Pathology Research and Practice 248, no. (2023): -.
Harvard	Babaei Z, Keyvanloo Shahrestanaki M, Aghaei M (2023) 'Mir-1236: Key Controller of Tumor Development and Progression: Focus on the Biological Functions and Molecular Mechanisms', Pathology Research and Practice, 248(), pp. -.
Vancouver	Babaei Z, Keyvanloo Shahrestanaki M, Aghaei M. Mir-1236: Key Controller of Tumor Development and Progression: Focus on the Biological Functions and Molecular Mechanisms. Pathology Research and Practice. 2023;248():-.
BibTex	@article{ author = {Babaei Z and Keyvanloo Shahrestanaki M and Aghaei M}, title = {Mir-1236: Key Controller of Tumor Development and Progression: Focus on the Biological Functions and Molecular Mechanisms}, journal = {Pathology Research and Practice}, volume = {248}, number = {}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Babaei Z AU - Keyvanloo Shahrestanaki M AU - Aghaei M TI - Mir-1236: Key Controller of Tumor Development and Progression: Focus on the Biological Functions and Molecular Mechanisms JO - Pathology Research and Practice VL - 248 IS - SP - EP - PY - 2023 ER -

Science Communicator Platform

Authors

Abstract