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Treatment of Intraoperative Sinus Tachycardia With Neostigmine Methylsulfate



Behaeen K1 ; Soltanzadeh M2 ; Pourmehdi Z3 ; Habibabadi MR4
Authors

Source: Life Science Journal Published:2012

Abstract

Background: Neostigmine is an anticholinestrase drug. Sometimes during operation, patient heart rate increased without known causes. Materials and Methods: We used intravenous neostigmine for control of sinus tachycardia during surgery. In this research 100 patients with class I, II ASA were selected within a period of time (29 months) for intraoperative treatment of sinus tachycardia. Results: The maximum effect of neostigmine in reducing heart rate were in 15 minutes after its injection with 29.3% and 29.4% reducing in heart rate of the patients with 1-12 y/o and 12-65 y/o respectively. Conclusion: The results of this study indicate intravenous injection of neostigmine in doses. o.o1mg/kg can be useful in reducing intraoperative unknown sinus tachycardia in patients with different ranges of age.
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