Nonsteroidal Anti-Inflammatory Drugs in Viral Infections Disease, Specially Covid-19 Publisher

Summary: Research suggests NSAIDs lack evidence in COVID-19 treatment, while corticosteroids may help early on. Should we rethink our approach to these drugs? #COVID19 #TreatmentGuidelines

Chamkouri N ; Absalan F ; Koolivand Z ; Yousefi M
Source: Advanced Biomedical Research Published:2023

Abstract

During the current SARS-CoV-2 (COVID-19) pandemic, some reports were presented based on those nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids may exacerbate symptoms in COVID-19 patients. According to this, we aimed to collate information available in published articles to identify any evidence behind these statements with the aim of helping clinicians on how best to treat patients. We could not find published conclusive evidence for or against the use of NSAIDs in COVID-19 patients. Meanwhile, there appeared to be some evidence that corticosteroids may be beneficial if utilized in the early acute phase of infection, however, conflicting WHO (World Health Organization) evidence surrounding corticosteroid use in certain viral infections means this evidence is not conclusive. Given the current availability of literature, caution should be exercised until further evidence emerges surrounding the use of NSAIDs and corticosteroids in COVID-19 patients. However, the availability of reliable information for clinicians and patients is paramount. © 2023 Elsevier B.V., All rights reserved.