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Characterization of Plga/Chitosan Electrospun Nano-Biocomposite Fabricated by Two Different Methods Publisher



Vaezifar S1, 2 ; Razavi S1 ; Golozar MA2 ; Esfahani HZ3 ; Morshed M4 ; Karbasi S5
Authors

Source: International Journal of Polymeric Materials and Polymeric Biomaterials Published:2015


Abstract

Nano-biocomposites composed of poly (lactide-co-glycolide) (PLGA) and chitosan (CS) were electrospun using two fabrication methods. In the single nozzle method, the CS nano-powders dispersed in PLGA solutions were electrospun through a single nozzle but in the double-nozzle method, PLGA and CS were simultaneously electrospun from two syringes and the electrospun PLGA nanofiber and electrosprayed CS nanoparticles were mixed and collected on the rotating drum (randomly oriented [A] and aligned [B]) to prepare the nano-biocomposite membrane. The PLGA/CS scaffolds were prepared at the different ratios. The single-nozzle method was associated with decreasing fiber diameter when the CS content was increased and exhibited improve mechanical and hydrophilic properties. © 2015 Taylor & Francis Group, LLC.
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