The Effect of Using Silver Diamine Fluoride at Two Different Times on the Microshear Bond Strength of Adhesives to Sound and Caries-Affected Dentin Publisher



Sadeghpour K ; Malekipour M ; Shirani F
Source: Dental Research Journal Published:2026

Abstract

Background: The aim of this laboratory study was to investigate the immediate and delayed effects of silver diamine fluoride (SDF) on the microshear bond strength (μSBS) of two types of sixth-generation self-etch and universal etch-and-rinse (ER) adhesives to sound dentin (SD) and Caries-Affected Dentin (CD). Materials and Methods: In this experimental study, 120 human third molars were selected, half of which had occlusal caries. First, the occlusal enamel was removed, and SD and CD surrounded by SD were exposed. The samples were divided into three groups. In the first group, SDF was not used; in the second group, SDF was applied, and in the third group, after applying SDF, the samples were incubated in artificial saliva for 1 month. The sixth-generation self-etch adhesive was used in half of the samples, and the universal ER adhesive was used in the other half. The μSBS of the samples was measured, and the strength and type of failure were investigated. The data were analyzed using three-way analysis of variance (α = 0.05). Results: The highest mean shear bond strength was observed in the SD without SDF and Clearfil Liner Bond (LB), and the lowest mean shear bond strength was observed in the CD, LB, and Aged SDF. The bond strength was lower in the CD than in the SD (P < 0.001). In CD, SDF caused a slight increase in the immediate μSBS, which was not significant in any of the bonding systems. Bond strength in the SD with Aged SDF was significantly higher in All Bond (AB) Universal than in LB (P = 0.03). Conclusion: Applying SDF to SD, regardless of the type of bond, decreases the bond strength, while it increases the bond strength of CD. If SDF is used in SD, it is better to use AB and ER bonding systems. © 2026 Dental Research Journal.