Bioelectrochemical Enhancement of Anaerobic Digestion Under Heavy Metal Stress: A Comparative Study of Ad and Ad-Mec Systems Publisher Pubmed



Arvin A ; Rezaalizadeh F ; Amin MM ; Hosseini M ; Darzi GN ; Ghasemi Y
Source: Biodegradation Published:2026

Abstract

Anaerobic digestion (AD) is a widely used technology for treating organic waste and producing renewable energy; however, environmental stresses, such as heavy-metal contamination, can significantly affect its stability. This study examines the potential of an integrated anaerobic digestion–microbial electrolysis cell (AD-MEC) system to enhance process resilience to heavy-metal toxicity. The performance of the AD-MEC was evaluated using cadmium (Cd2⁺), copper (Cu2⁺), nickel (Ni2⁺), iron (Fe2⁺), chromium (Cr2⁺), and zinc (Zn2⁺), and compared with that of a conventional AD system. The AD-MEC system exhibited greater resistance to heavy-metal inhibition, achieving higher maximum chemical oxygen demand (COD) removal efficiency and methane content than the conventional AD system. The order of heavy-metal inhibition was Zn2⁺ > Cu2⁺ > Cr2⁺ > Ni2⁺ > Cd2⁺ > Fe2⁺ for the traditional AD and Cu2 > Cr2+ for the AD-MEC. These results highlight the potential of bioelectrochemical integration to enhance the robustness of anaerobic digestion under heavy-metal stress. © The Author(s), under exclusive licence to Springer Nature B.V. 2026.