Fyodorov-Zuev Keratoprosthesis Implantation: Long-Term Results in Patients With Multiple Failed Corneal Grafts Publisher Pubmed



Ghaffariyeh A¹ ; Honarpisheh N¹ ; Karkhaneh A² ; Abudi R¹ ; Moroz ZI³ ; Peyman A⁴ ; Faramarzi A⁵ ; Abasov F⁶
Source: Graefe's Archive for Clinical and Experimental Ophthalmology Published:2011

Abstract

Background: The long term results of the Fyodorov-Zuev keratoprosthesis are presented for ten patients with repeated graft failures. Methods: The study took place at Dr Khodadoust Eye Hospital. The Fyodorov-Zuev keratoprosthesis was implanted in ten patients with repeated graft failures, including seven patients with old trachoma, two patients with chemical injury, and a patient with thermal injury. The outcome measures were visual acuity, retention, and complications of the keratoprosthesis. Results: Preoperative best-uncorrected visual acuity (BUVA) ranged from counting fingers to light perception (median: light perception). The keratoprosthesis dramatically improved vision in most patients. Patients retained BUVA of 20/200-20/50 in 50%, 20/60-20/100 in 30%, 20/200 in 10% and 20/400 in 10%. Overall, 90% had 1 year postoperative vision of 20/200 or better. 70% of cases had BUVA of 20/200 or better at the last follow-up (average 52 months). Of ten keratoprosthesis implanted, three have been removed, and as a result, retention rate was 70% during average follow-up of 52 months .The most common postoperative complications were retroprosthetic membrane formation (40%), uveitis (20%), glaucoma (20%), tissue overgrowth (20%), early leakage (20%), late leakage (20%), aseptic necrosis (20%), retinal detachment (10%), endophthalmitis (10%), and granulation tissue growth (10%). Conclusions: Fyodorov-Zuev keratoprosthesis is an effective means of managing repeated corneal graft failure. © 2010 Springer-Verlag.