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Application of Systemic Inflammation Score for the Assessment of Contrast-Induced Acute Kidney Injury; a Review Publisher



Mirfendereski S1 ; Taghipour M2 ; Yadollahi F3 ; Taghavinejad H4 ; Ahmadnia M4
Authors

Source: Journal of Nephropathology Published:2024


Abstract

Contrast-related acute renal failure is a multifactorial condition that involves oxidative stress, inflammation, and direct tubular toxicity. Risk factors for contrast-induced nephropathy comprise pre-existing kidney dysfunction, diabetes mellitus, advanced age, congestive heart failure, hypotension, anemia, and volume depletion. Preventive measures include identifying high-risk patients and implementing preventive measures such as adequate hydration, minimizing contrast use, and avoiding using contrast media in patients with pre-existing renal dysfunction. The systemic inflammation score is a promising tool for predicting contrast-associated acute kidney injury (CA-AKI) in patients undergoing contrast-enhanced imaging procedures. Further studies are needed to validate the use of SIS in clinical practice and to better understand the underlying mechanisms of inflammation in (CA-AKI). © 2024 The Author(s);.
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