Gut Microbiota: A Perspective of Precision Medicine in Endocrine Disorders Publisher



Shirvani Rad S^{1, 2} ; Nikkhah A³ ; Orvatinia M³ ; Ejtahed HS^{4, 5} ; Sarhangi N² ; Jamaldini SH⁶ ; Khodayari N⁷ ; Aghaei Meybodi HR² ; Hasanzad M^{2, 6}
Source: Journal of Diabetes and Metabolic Disorders Published:2020

Abstract

Gut microbiota composition is unique in every individual, it impacts on organ functions that produce hormones. Gut microbiota composition balance is directly related to our general health status. This continual interaction between gut microbiota and endocrine organs sometimes can be considered as the etiology of diseases such as type 2 diabetes mellitus (T2DM), obesity, osteoporosis, polycystic ovary syndrome (PCOS), and thyroid diseases. Microbiota is introduced for a total collection of microbial organisms in our bodies and microbiome referred for their genome and their collective functions. Near 100 trillion microorganisms live in our body and almost all of them occupy the human gut gastrointestinal tract. Precision medicine can play a crucial role in health maintenance by affecting gut microbiota composition in every individual. It can also develop special treatments specifically for every individual. In this review, we addressed any correlation between gut microbiota and endocrine disorders including T2DM, obesity, PCOS, thyroid disorders and osteoporosis. © 2020, Springer Nature Switzerland AG.