Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
An Eco-Friendly Synthesis of 4-Aryl-Substituted Pyrano-Fuzed Coumarins As Potential Pharmacological Active Heterocycles Using Molybdenum Oxide Nanoparticles As an Effective and Recyclable Catalyst Publisher



Pourshojaei Y1, 2 ; Jadidi MH1 ; Eskandari K1 ; Foroumadi A2, 3 ; Asadipour A1
Authors

Source: Research on Chemical Intermediates Published:2018


Abstract

A green cascade three-component reaction between 4-hydroxycoumarin, malononitrile and a wide range of arylaldehydes by employing molybdenum oxide nanoparticles (MoO3 NPs) is described. By this achievement, some medicinally important products have been successfully synthesized in a one-pot under green conditions. Obtaining good to excellent yields of products, environmentally benign procedure, being easily handled, availability of starting materials, use of non-toxic solvents, and high recyclability of nano-catalysts are the most important advantages of this methodology. © 2018, Springer Science+Business Media B.V., part of Springer Nature.