Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Clonal Relation and Antimicrobial Resistance Pattern of Extended-Spectrum Β-Lactamase- and Ampc Β-Lactamase-Producing Enterobacter Spp. Isolated From Different Clinical Samples in Tehran, Iran Publisher Pubmed



Ghanavati R1 ; Emaneini M1 ; Kalantarneyestanaki D2 ; Maraji AS1 ; Dalvand M1 ; Beigverdi R1 ; Jabalameli F1
Authors

Source: Revista da Sociedade Brasileira de Medicina Tropical Published:2018


Abstract

Introduction: Here, we determined the genes encoding antibiotic resistance enzymes and virulence factors and evaluated the genetic relationship between Enterobacter spp. isolated from different clinical samples. Methods: A total of 57 clinical isolates of Enterobacter spp. were tested for the production of extended-spectrum β-lactamases (ESBLs), carbapenemase, and AmpC using phenotypic and genotypic methods. Results: The most common ESBLs and AmpC β-lactamases were blaTEM (63.3%) and blaEBC (57.7%), respectively. The most prevalent virulence gene was rpos (87.7%). The random amplified polymorphic DNA (RAPD) patterns of strains were genetically unrelated. Conclusions: RAPD polymerase chain reaction analysis revealed high genetic diversity among isolates. © 2018, Sociedade Brasileira de Medicina Tropical. All rights reserved.
Related Docs
View other Related Docs
1. Evaluation of Fosfomycin Activity Against Extended Spectrum Beta Lactamase (Esbl) Producing Enterobacteriaceae Isolated From Three Centers of Tehran, Iran, Recent Patents on Anti-Infective Drug Discovery (2018)
2. Molecular Analysis and Antimicrobial Resistance Pattern of Distinct Strains of Pseudomonas Aeruginosa Isolated From Cystic Fibrosis Patients in Iran, Iranian Journal of Microbiology (2019)
3. Antimicrobial Susceptibility Patterns of Enteroaggregative E. Coli, As the Most Common Diarrheagenic E. Coli, Associated to Gastroenteritis Outbreaks in Iran, Archives of Pediatric Infectious Diseases (2018)
Experts (# of related papers)
View all Related Experts
Mohammad Mehdi Soltan Dallal (3)
Fereshteh Jabalameli (3)
Other Related Docs
4. Biofilm Formation, Antimicrobial Resistance Genes, and Genetic Diversity of Salmonella Enterica Subspecies Enterica Serotype Enteritidis Isolated From Food and Animal Sources in Iran, Journal of Global Antimicrobial Resistance (2023)
5. Determination of the Frequency of Β-Lactamase Genes (Bla Shv, Bla Tem, Bla Ctx-M) and Phylogenetic Groups Among Esbl-Producing Uropathogenic Escherichia Coli Isolated From Outpatients, Journal of Laboratory Medicine (2020)
6. Prevalence of Extended-Spectrum-Β-Lactamase-Producing Escherichia Coli Isolates Among Uropathogensin a Pediatrics Hospital, Der Pharma Chemica (2016)
7. An Investigation of Extended-Spectrum Β-Lactamases (Esbls) in Klebsiella Isolated From Foodborne Outbreaks in Iran, Gene Reports (2020)
8. The Diversity of Class B and Class D Carbapenemases in Clinical Acinetobacter Baumannii Isolates, Infezioni in Medicina (2018)
9. Evaluating the Antimicrobial Resistance and Frequency of Ampc Β-Lactamases Blacmy-2 Gene in Gram-Negative Bacteria Isolates Collected From Selected Hospitals of Iran: A Multicenter Retrospective Study, Gene Reports (2020)
10. Association Between Presence of Rmpa, Mrka and Mrkd Genes and Antibiotic Resistance in Clinical Klebsiella Pneumoniae Isolates From Hospitals in Tehran, Iran, Iranian Journal of Public Health (2021)
11. Clonal Relationship and Resistance Profiles Among Esbl-Producing Escherichia Coli, Frontiers in Cellular and Infection Microbiology (2021)
12. Survey of Various Carbapenem-Resistant Mechanisms of Acinetobacter Baumannii and Pseudomonas Aeruginosa Isolated From Clinical Samples in Iran, Iranian Journal of Basic Medical Sciences (2020)
13. Evaluation of Carbapenemase-Resistant Enterobacteriaceae by Disk Diffusion Test and Polymerase Chain Reaction, Journal of Iranian Medical Council (2024)
14. Frequency of Extended-Spectrum Beta-Lactamase Genes and Antibiotic Resistance Patterns of Gram-Negative Bacteria in Iran: A Multicenter Study, Gene Reports (2020)
15. Molecular Study of Carbapenemase Genes in Clinical Isolates of Enterobacteriaceae Resistant to Carbapenems and Determining Their Clonal Relationship Using Pulsed-Field Gel Electrophoresis, Journal of Medical Microbiology (2017)
16. Phenotypic and Genotypic Detection of Ampc and Esbl Beta-Lactamase Resistance in Escherichia Coli Strains Isolated From Patients With Urinary Tract Infections, Journal of Knowledge and Health in Basic Medical Sciences (2023)
17. Evaluation of the Β-Lactamase Disk Test Method in the Detection of Extended-Spectrum-Β-Lactamases in Clinical Isolates of Multidrug-Resistant Pseudomonas Aeruginosa, Journal of Kerman University of Medical Sciences (2016)
18. Wide Distribution of Carbapenem Resistant Acinetobacter Baumannii in Burns Patients in Iran, Frontiers in Microbiology (2015)
19. Comparative Genome Analysis of Colistin-Resistant Oxa-48-Producing Klebsiella Pneumoniae Clinical Strains Isolated From Two Iranian Hospitals, Annals of Clinical Microbiology and Antimicrobials (2021)
20. Antibiotic Resistance Pattern and Frequency of Shv, Ctx, Tem, and Oxa Resistance Gene Among Salmonella Serotypes, Health Biotechnology and Biopharma (2022)