Tehran University of Medical Sciences

Science Communicator Platform

Share By
Optimizing Laccase Selection for Enhanced Outcomes: A Comprehensive Review Publisher



Abdi Dezfouli R1 ; Esmaeilidezfouli E2
Authors

Source: 3 Biotech Published:2024


Abstract

Despite their widespread applications in sectors such as pulp and paper, textile, food and beverage, pharmaceuticals, and biofuel production, laccases encounter challenges related to their activity and stability under varying reaction conditions. This review accumulates data on the complex interplay between laccase characteristics and reaction conditions for maximizing their efficacy in diverse biotechnological processes. Benefits of organic media such as improved substrate selectivity and reaction control, and their risks such as enzyme denaturation and reduced activity are reported. Additionally, the effect of reaction conditions such as pH and temperature on laccase activity and stability are gathered and reported. Sources like Bacillus pumilus, Alcaligenes faecalis, Bacillus clausii, and Bacillus tequilensis SN4 are producing laccases that are both thermo-active and alkali-active. Additionally, changes induced by the presence of various substances within reaction media such as metals, inhibitors, and organic solvents are also reported. Bacillus pumilus and Bacillus licheniformis LS04 produce the most resistant laccases in this case. Finally, the remarkable laccases have been highlighted and the proper laccase source for each industrial application is suggested. © King Abdulaziz City for Science and Technology 2024.
Related Docs
View other Related Docs
1. Insights Into Laccase Producing Organisms, Fermentation States, Purification Strategies, and Biotechnological Applications, Biotechnology Progress (2015)
2. Biomedical and Pharmaceutical-Related Applications of Laccases, Current Protein and Peptide Science (2020)
3. Laccase-Mediated Treatment of Pharmaceutical Wastes, Research Advancements in Pharmaceutical# Nutritional# and Industrial Enzymology (2018)
Experts (# of related papers)
View all Related Experts
Mohammad Ali Faramarzi (16)
Somayeh Mojtabavi (6)
Other Related Docs
4. Enhanced Production, One-Step Affinity Purification, and Characterization of Laccase From Solid-State Culture of Lentinus Tigrinus and Delignification of Pistachio Shell by Free and Immobilized Enzyme, Journal of Environmental Management (2019)
5. Delignification and Detoxification of Peanut Shell Bio-Waste Using an Extremely Halophilic Laccase From an Aquisalibacillus Elongatus Isolate, Extremophiles (2017)
6. Improved Production and Characterization of a Highly Stable Laccase From the Halophilic Bacterium Chromohalobacter Salexigens for the Efficient Delignification of Almond Shell Bio-Waste, International Journal of Biological Macromolecules (2017)
7. In the Pursuit of an Efficient Delignification From Pumpkin Seed Shells by the Polyextremophilic and Laccase-Producing Bacterial Isolate Halomonas Elongata, Biomass Conversion and Biorefinery (2025)
8. Combination of Thermal and Biological Treatments for Bio-Removal and Detoxification of Some Recalcitrant Synthetic Dyes by Betaine-Induced Thermostabilized Laccase, Environmental Technology and Innovation (2020)
9. Elimination and Detoxification of Phenanthrene Assisted by a Laccase From Halophile Alkalibacillus Almallahensis, Journal of Environmental Health Science and Engineering (2022)
10. Molecular Level Insight Into Stability, Activity, and Structure of Laccase in Aqueous Ionic Liquid and Organic Solvents: An Experimental and Computational Research, Journal of Molecular Liquids (2020)
11. Application of Free and Immobilized Laccase for Removal and Detoxification of Fluoroquinolones From Aqueous Solution, Global Nest Journal (2020)
12. A New Probiotic Lactobacillus Plantarum Strain Isolated From Traditional Dairy Together With Nanochitosan Particles Shows the Synergistic Effect on Aflatoxin B1 Detoxification, Archives of Microbiology (2022)
13. A Novel Halophilic Laccase From Halomonas Elongata: Purification, Characterization, and Application in Green Synthesis of Salicylic Acid, International Journal of Biological Macromolecules (2025)
14. Application of Cultivable Lactic Acid Bacteria Isolated From Iranian Traditional Dairy Products for the Production of Liquid and Dried Kashks, LWT (2019)
15. Magnetic Casein Aggregates As an Innovative Support Platform for Laccase Immobilization and Bioremoval of Crystal Violet, International Journal of Biological Macromolecules (2022)
16. Rational Design Toward Developing a More Efficient Laccase: Catalytic Efficiency and Selectivity, International Journal of Biological Macromolecules (2018)
17. Isolation, One-Step Affinity Purification, and Characterization of a Polyextremotolerant Laccase From the Halophilic Bacterium Aquisalibacillus Elongatus and Its Application in the Delignification of Sugar Beet Pulp, Bioresource Technology (2017)
18. Study of Laccase Activity and Stability in the Presence of Ionic and Non-Ionic Surfactants and the Bioconversion of Indole in Laccase-Tx-100 System, Journal of Molecular Catalysis B: Enzymatic (2016)
19. Innovative Application of Laccase Enzyme in Food Packaging, Trends in Food Science and Technology (2024)
20. Enhanced Laccase Production by Paramyrothecium Roridum Under Solid-State Fermentation: Application in Neutral-Ph Delignification and Valorization of Acorn Shells, International Journal of Biological Macromolecules (2025)