Metal-Free Regioselective C5-Cyanoalkylation of the 8-Aminoquinolineamides/Sulfonamides: Via Oxidative Cross-Dehydrogenative Coupling With Alkylnitriles

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Metal-Free Regioselective C5-Cyanoalkylation of the 8-Aminoquinolineamides/Sulfonamides: Via Oxidative Cross-Dehydrogenative Coupling With Alkylnitriles Publisher

Doraghi F¹ ; Kianmehr E¹ ; Foroumadi A²

Source: Organic Chemistry Frontiers Published:2021

Abstract

A direct metal-free oxidative cross-dehydrogenative coupling of 8-aminoquinolineamides/sulfonamides and acetonitrile is described. This protocol exhibits good tolerance toward various aryl, heteroaryl and aliphatic carboxamide derivatives. Mechanism investigations reveal that the reaction proceeds via a radical pathway. © the Partner Organisations.

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Style	Citing Format
MLA	Doraghi F, Kianmehr E, Foroumadi A. "Metal-Free Regioselective C5-Cyanoalkylation of the 8-Aminoquinolineamides/Sulfonamides: Via Oxidative Cross-Dehydrogenative Coupling With Alkylnitriles." Organic Chemistry Frontiers, vol. 8, no. 19, 2021, pp. 5424-5431.
APA	Doraghi F, Kianmehr E, Foroumadi A (2021). Metal-Free Regioselective C5-Cyanoalkylation of the 8-Aminoquinolineamides/Sulfonamides: Via Oxidative Cross-Dehydrogenative Coupling With Alkylnitriles. Organic Chemistry Frontiers, 8(19), 5424-5431.
Chicago	Doraghi F, Kianmehr E, Foroumadi A. "Metal-Free Regioselective C5-Cyanoalkylation of the 8-Aminoquinolineamides/Sulfonamides: Via Oxidative Cross-Dehydrogenative Coupling With Alkylnitriles." Organic Chemistry Frontiers 8, no. 19 (2021): 5424-5431.
Harvard	Doraghi F, Kianmehr E, Foroumadi A (2021) 'Metal-Free Regioselective C5-Cyanoalkylation of the 8-Aminoquinolineamides/Sulfonamides: Via Oxidative Cross-Dehydrogenative Coupling With Alkylnitriles', Organic Chemistry Frontiers, 8(19), pp. 5424-5431.
Vancouver	Doraghi F, Kianmehr E, Foroumadi A. Metal-Free Regioselective C5-Cyanoalkylation of the 8-Aminoquinolineamides/Sulfonamides: Via Oxidative Cross-Dehydrogenative Coupling With Alkylnitriles. Organic Chemistry Frontiers. 2021;8(19):5424-5431.
BibTex	@article{ author = {Doraghi F and Kianmehr E and Foroumadi A}, title = {Metal-Free Regioselective C5-Cyanoalkylation of the 8-Aminoquinolineamides/Sulfonamides: Via Oxidative Cross-Dehydrogenative Coupling With Alkylnitriles}, journal = {Organic Chemistry Frontiers}, volume = {8}, number = {19}, pages = {5424-5431}, year = {2021} }
RIS	TY - JOUR AU - Doraghi F AU - Kianmehr E AU - Foroumadi A TI - Metal-Free Regioselective C5-Cyanoalkylation of the 8-Aminoquinolineamides/Sulfonamides: Via Oxidative Cross-Dehydrogenative Coupling With Alkylnitriles JO - Organic Chemistry Frontiers VL - 8 IS - 19 SP - 5424 EP - 5431 PY - 2021 ER -

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