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Nanoparticles: Novel Vehicles in Treatment of Glioblastoma Publisher Pubmed



Pourgholi F1, 2, 3 ; Hajivalili M1, 2, 3 ; Farhad JN4 ; Kafil HS3 ; Yousefi M2, 3
Authors

Source: Biomedicine and Pharmacotherapy Published:2016


Abstract

Glioblastoma multiform (GBM) is the most common brain tumor. The current GBM treatments comprise of radiation therapy, chemotherapy and surgery. One of the most important problems regarding the treatment of GBM is the presence of blood brain barrier (BBB) which inhibits the efficient drug delivery into central nervous system (CNS). Nanothechnology can help to deliver therapeutic drugs into CNS through crossing the BBB. There are different types of nanoparticles (Nps) which can be manipulated for clinical applications as a treatment for CNS-related disorders. In this review, we will discuss the role of Nps in the treatment of GBM. © 2015.
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